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Notch Receptor Intracellular Domain

Known as: Neurogenic Locus Notch Homolog Protein Intracellular Domain, Notch ICD, Notch Intracellular Domain 
The free carboxy-terminal intracellular domain (ICD) of a notch family protein, which is a product of regulated intramembrane proteolysis mediated by… 
National Institutes of Health

Related topics

Related topics

1 relation
Transcriptional Regulation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
A Role for the Primary Cilium in Notch Signaling and Epidermal Differentiation during Skin Development
Highly Cited
2008
Highly Cited
2008
Interaction between Reelin and Notch Signaling Regulates Neuronal Migration in the Cerebral Cortex
Highly Cited
2006
Highly Cited
2006
PTF1 Is an Organ-Specific and Notch-Independent Basic Helix-Loop-Helix Complex Containing the Mammalian Suppressor of Hairless (RBP-J) or Its Paralogue, RBP-L
ABSTRACT PTF1 is a trimeric transcription factor essential to the development of the pancreas and to the maintenance of the… 
Highly Cited
2005
Highly Cited
2005
Two contrasting roles for Notch activity in chick inner ear development: specification of prosensory patches and lateral inhibition of hair-cell differentiation
Lateral inhibition mediated by Notch is thought to generate the mosaic of hair cells and supporting cells in the inner ear, but… 
Highly Cited
2003
Highly Cited
2003
NAD-induced T cell death: ADP-ribosylation of cell surface proteins by ART2 activates the cytolytic P2X7 purinoceptor.
Highly Cited
2002
Highly Cited
2002
Notch activation during endothelial cell network formation in vitro targets the basic HLH transcription factor HESR-1 and downregulates VEGFR-2/KDR expression.
Angiogenesis is essential for normal homeostasis, wound healing, and tumor growth and involves a switch in endothelial cell (EC… 
Highly Cited
2002
Highly Cited
2002
Glycogen Synthase Kinase-3β Modulates Notch Signaling and Stability
Highly Cited
2001
Highly Cited
2001
Novel Notch alleles reveal a Deltex-dependent pathway repressing neural fate
Highly Cited
2000
Highly Cited
2000
Presenilins are required for γ-secretase cleavage of β-APP and transmembrane cleavage of Notch-1
Presenilins are required for γ -secretase cleavage of β -APP and transmembrane cleavage of Notch-1 
Highly Cited
2000
Highly Cited
2000
Total inactivation of γ–secretase activity in presenilin-deficient embryonic stem cells
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