FAQ

Nonsteroidal Anti-Androgens

Known as: Anti-Androgens, Nonsteroidal, AntiAndrogens, Nonsteroidal, Nonsteroidal Anti Androgens 
Nonsteroidal agents which block the action or downregulate the synthesis of ANDROGENS.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1979-2017
0519792017

Related topics

Related topics

5 relations
In Bloodagonistschemical synthesisisolation & purification analysis
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Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Nonsteroidal Anti-Androgens
In Blood
chemical synthesis
standards characteristics
agonists
isolation & purification analysis

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
Development of a second-generation antiandrogen for treatment of advanced prostate cancer.
Metastatic prostate cancer is treated with drugs that antagonize androgen action, but most patients progress to a more aggressive… (More)
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Highly Cited
2008
Highly Cited
2008
Alternative nonsteroidal antiandrogen therapy for advanced prostate cancer that relapsed after initial maximum androgen blockade.
PURPOSE Large meta-analyses have documented that maximum androgen blockade with nonsteroidal antiandrogens for advanced prostate… (More)
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2004
2004
Alternative antiandrogens to treat prostate cancer relapse after initial hormone therapy.
PURPOSE We studied the efficiency of second or third line hormonal therapy for prostate cancer relapse after hormone therapy… (More)
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2003
2003
UV filters with antagonistic action at androgen receptors in the MDA-kb2 cell transcriptional-activation assay.
The fact that certain ultraviolet (UV) filters used in cosmetics display estrogenic activity prompted us to study potential… (More)
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Highly Cited
2003
Highly Cited
2003
Androgens stimulate hypoxia-inducible factor 1 activation via autocrine loop of tyrosine kinase receptor/phosphatidylinositol 3'-kinase/protein kinase B in prostate cancer cells.
PURPOSE Androgen deprivation is implicated in reducing neoangiogenesis in prostate cancer (PCA). Androgens regulate the… (More)
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1997
1997
Maximum androgen blockade in advanced prostate cancer: a meta-analysis of published randomized controlled trials using nonsteroidal antiandrogens.
OBJECTIVES To assess the survival benefit of maximum androgen blockade (MAB) using nonsteroidal antiandrogens (NSAAs) through… (More)
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1995
1995
Dramatic prostate specific antigen decrease in response to discontinuation of megestrol acetate in advanced prostate cancer: expansion of the antiandrogen withdrawal syndrome.
We report a dramatic decrease in prostate specific antigen in response to the discontinuation of megestrol acetate in a patient… (More)
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Highly Cited
1993
Highly Cited
1993
Mutant androgen receptor detected in an advanced-stage prostatic carcinoma is activated by adrenal androgens and progesterone.
Structural changes of the androgen receptor (AR) may contribute to the development of resistance to endocrine therapy in… (More)
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1993
1993
Transcriptional and posttranscriptional regulation of human androgen receptor expression by androgen.
Autoregulation is a control mechanism common to several proteins of the steroid/thyroid hormone receptor superfamily. In this… (More)
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1981
1981
Receptor binding and biological activity of steroidal and nonsteroidal antiandrogens.
 
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