Nonachlazine

Known as: Nonachlazin, 10H-Phenothiazine, 2-chloro-10-(3-(hexahydropyrrolo(1,2-a)pyrazin-2(1H)-yl)-1-oxopropyl)-, dihydrochloride, Azaclorzine 
Coronary vasodilator with a novel mechanism of action; proposed as antianginal agent.

Topic mentions per year

Topic mentions per year

1975-2004
0519752004

Papers overview

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2004
2004
The coronary blood flow in anesthetized and unanesthetized dogs was measured by means of an ultrasonic Doppler radiotelemetric… (More)
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2004
2004
Nonachlazine, a new Soviet antianginal preparation, has a marked action on central and peripheral adrenergic processes [3, 5, 6… (More)
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2004
2004
Nonachlazine (10 mg/kg, intravenously) has a biphasic effect on cardiac activity. A short phase of weakening of cardiac activity… (More)
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1980
1980
Nonachlazin binds in vitro heparin in blood plasma and aqueous medium. This interaction complies with logarithmic dependence… (More)
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1980
1980
It has been shown that nonachlazin in a dose of 6 mg/kg injected intravenously to cats 15 minutes after occlusion of the left… (More)
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1980
1980
Nonachlazin diminishes aseptic inflammation provoked by subplantar administration of carrageenin to rats. Nonachlazin increases… (More)
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1979
1979
Nonachlazine infused in the form of a solution penetrates rapidly the blood and organs. In experiments on cats it was shown that… (More)
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1977
1977
Coronary circulation was measured in the anesthetized and nonanesthetized dogs by means of ultrasonic Doppler's radiotelemetric… (More)
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1976
1976
Experimental data on the mechanism accounting for the action of a new antianginal drug nonachlazine are presented. Nonachlazine… (More)
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1976
1976
Nonachlazine (2 micrometer) blocked significantly the uptake 1 of endogenic noradrenaline in the myocardial tissues and in… (More)
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