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Nonachlazine

Known as: Nonachlazin, 10H-Phenothiazine, 2-chloro-10-(3-(hexahydropyrrolo(1,2-a)pyrazin-2(1H)-yl)-1-oxopropyl)-, dihydrochloride, AZACLORZINE 
Coronary vasodilator with a novel mechanism of action; proposed as antianginal agent.
National Institutes of Health

Related topics

Related topics

8 relations
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Broader (1)

Vasodilator Agents

Papers overview

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2004
2004
Effect of psychotropic drugs on synaptosomal uptake of H3-γ-aminobutyric acid and on Na,K-ATPase activity
Neurotropic drugs belonging to various groups (fluphenazine, nonachlazine, trifluperidol fluacizine, imipramine, diazepam… 
1985
1985
[Effect of nonachlazine on the temperature sensitivity of the lysosomal membranes of the heart muscle in rats in vitro].
It has been shown in vitro that nonachlazine stabilizes rat myocardial lysosomal membranes and activates total acid phosphatase… 
1984
1984
Azacycloalkanes. XXVII. Synthesis and antianginal activity of nonachlazine stereoisomers
The preparation nonachlazine, which is the dihydrochloride of 10-[~-N-(l,4-diazabicyclo [4.3.0]nonanyl)propionyl]-2… 
1983
1983
On the mechanism of action of the antianginal drug nonachlazine on ischemic myocardium.
The activity of a new antianginal drug, nonachlazine, synthetized in the Institute of Pharmacology, Academy of Medical Sciences… 
1981
1981
[Blood rheological effects in ischemic heart disease treated with antianginal and thrombolytic agents].
In 161 patients with different forms of ischaemic heart disease the authors studied changes of the blood viscosity, erythrocyte… 
1980
1980
Effect of nonachlazine on ATP, ADP, and lactic acid concentrations in the intact and ischemized myocardium
: It has been shown that nonachlazin in a dose of 6 mg/kg injected intravenously to cats 15 minutes after occlusion of the left… 
1980
1980
[Wolfram's syndrome].
1978
1978
[Comparison of the effect of ildamen and nonachlazin on the blood supply and activities of the heart].
Instravenous infusion of ildamen (0.8-1 mg/kg) into anesthesized cats caused an increase in coronary blood flow and oxygen… 
1977
1977
Assessment of the safety of nonachlazin during long term administration
1976
1976
Effect of nonachlazine on the processes of uptake and release of nordrenaline
: Nonachlazine (2 micrometer) blocked significantly the uptake 1 of endogenic noradrenaline in the myocardial tissues and in… 
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