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Nik 12192

Known as: Nik-12192, Nik12192 
National Institutes of Health

Papers overview

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2006
2006
Effect of a Novel Vacuolar-H+-ATPase Inhibitor on Cell and Tumor Response to Camptothecins
The vacuolar-H+-ATPase, functionally expressed in cell membranes, is known to play a relevant role in intracellular pH regulatory… 
2006
2006
A novel inhibitor of vacuolar H+-ATPase, NIK-12192, potentiates the antitumor effect of topotecan in BCRP-expressing tumor systems.
Proc Amer Assoc Cancer Res, Volume 47, 2006 5422 Tumor cells often exist in hypoxic microenvironment and produce acidic… 
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