Neutral Ceramidase

Known as: NCDase, LCDase, hCD 
A ceramidase subtype that is active at neutral pH. It is found at high levels within the SMALL INTESTINE and in the BRAIN.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1981-2017
05101519812017

Papers overview

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2016
2016
Alterations in sphingolipid metabolism, especially ceramide and sphingosine 1-phosphate, have been linked to colon cancer… (More)
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2013
2013
We present a peptide library and data resource of >100,000 synthetic, unmodified peptides and their phosphorylated counterparts… (More)
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2009
2009
Gemcitabine (GMZ) is a chemotherapeutic agent with well established effects on cell growth arrest and apoptosis. In this study… (More)
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2006
2006
Complex sphingolipids are abundant as eukaryotic cell membrane components, whereas their metabolites, in particular ceramide… (More)
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2005
2005
We previously reported that rat and mouse neutral ceramidases were mainly localized to plasma membranes as a type II integral… (More)
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2004
2004
Almost all observations on the functions of neutral ceramidase have been carried out at cellular levels but not at an individual… (More)
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2003
2003
The sphingolipid, ceramide, is a natural dietary constituent and a potent mediator of apoptosis. If left undegraded, it may… (More)
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2002
2002
We report here the molecular cloning and characterization of the Drosophila neutral ceramidase (CDase). Using the BLAST program… (More)
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2001
2001
Previously, we reported two types of neutral ceramidase in mice, one solubilized by freeze-thawing and one not. The former was… (More)
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2001
2001
Ceramide plays an important role in regulating cell proliferation and apoptosis. Recent studies indicate that generation of… (More)
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