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Neutral Ceramidase

Known as: NCDase, LCDase, hCD 
A ceramidase subtype that is active at neutral pH. It is found at high levels within the SMALL INTESTINE and in the BRAIN.
National Institutes of Health

Related topics

Related topics

15 relations
ASAH2 geneEnzyme GeneHydrolysisIn Blood

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Loss of neutral ceramidase protects cells from nutrient- and energy -deprivation-induced cell death.
Sphingolipids are a family of lipids that regulate the cell cycle, differentiation and cell death. Sphingolipids are known to… 
2014
2014
HCD-only fragmentation method balances peptide identification and quantitation of TMT-labeled samples in hybrid linear ion trap/orbitrap mass spectrometers.
2010
2010
The effect of high-fat diet on the sphingolipid pathway of signal transduction in regenerating rat liver.
2008
2008
Chronic activation of neutral ceramidase protects β-cells against cytokine-induced apoptosis
AbstractAim:To investigate the activity and expression of neutral ceramidase (N-CDase) in the insulin-secreting cell line INS-1… 
2007
2007
A novel gene derived from a segmental duplication shows perturbed expression in Alzheimer’s disease
Alzheimer’s disease (AD) is a disabling neurodegenerative disorder with onset commonly in late life. Three genes have been… 
2006
2006
Amlodipine treatment reduces stroke size in apolipoprotein E-deficient mice.
2005
2005
Protein transduction with bacterial cytosine deaminase fused to the TLM intercellular transport motif induces profound chemosensitivity to 5-fluorocytosine in human hepatoma cells.
2004
2004
Cloning of soybean genes induced during hypersensitive cell death caused by syringolide elicitor
Syringolide elicitors produced by bacteria expressing Pseudomonas syringae pv. glycinea avirulence gene D (avrD) induce… 
2003
2003
Neutral ceramidase gene: role in regulating ceramide-induced apoptosis.
Highly Cited
2001
Highly Cited
2001
Structural requirements of ceramide and sphingosine based inhibitors of mitochondrial ceramidase.
The effects of structural analogues of ceramide on rat brain mitochondrial ceramidase (mt-CDase) were investigated. Design of… 
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