FAQ

Nephroblastoma Overexpressed Protein

Known as: NOVH Protein, CCN3 Protein, Nephroblastoma Overexpressed Protein [Chemical/Ingredient] 
A CCN protein family member found at high levels in NEPHROBLASTOMA cells. It is found both intracellularly and in the EXTRACELLULAR MATRIX and may… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1999-2018
02419992018

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Related topics

9 relations
In BloodProcess of secretionagonistsantagonists & inhibitors
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NOV protein, human

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Nephroblastoma Overexpressed Protein
physiological aspects
In Blood
chemical synthesis
standards characteristics
Process of secretion

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
CCN3 secretion is regulated by palmitoylation via ZDHHC22.
Normal extracellular secretion of nephroblastoma overexpressed (NOV, also known as CCN3) is important for the adhesion, migration… (More)
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2016
2016
Adenoviral CCN gene transfers induce in vitro and in vivo endoplasmic reticulum stress and unfolded protein response.
The endoplasmic reticulum (ER) is primarily recognized as the site of synthesis and folding of secreted membrane-bound and… (More)
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2015
2015
Expression of CCN family members correlates with the clinical features of hepatocellular carcinoma.
Studies have reported that the CCN family of proteins plays an important role in stimulating tumorigenesis. However, the… (More)
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2015
2015
Identification of a mutation in the WISP3 gene in three unrelated families with progressive pseudorheumatoid dysplasia.
Progressive pseudorheumatoid dysplasia (PPD) is a rare autosomal recessive genetic disease, which is caused by the functional… (More)
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2012
2012
CCN3 increases cell motility and ICAM-1 expression in prostate cancer cells.
Nephroblastoma overexpressed (NOV or CCN3) is a secreted matrix-associated protein that belongs to the CCN gene family and is… (More)
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2008
2008
The CCN3 gene coding for an extracellular adhesion-related protein is transcriptionally activated by the p53 tumor suppressor.
The CCN3 protein (Nov, Nephroblastoma overexpressed) is a member of the CCN family (Cyr61, CTGF, Nov) of growth regulators and… (More)
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Review
2007
Review
2007
CCN2, the connective tissue growth factor
  • F. Luft
  • Journal of Molecular Medicine
  • 2007
The role of extracellular matrix proteins in signaling control and regulation of response to injury, particularly in terms of… (More)
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Highly Cited
2007
Highly Cited
2007
NOV (CCN3) functions as a regulator of human hematopoietic stem or progenitor cells.
Clinically successful hematopoietic cell transplantation is dependent on hematopoietic stem and progenitor cells. Here we… (More)
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2003
2003
NOV (CCN3) regulation in the growth plate and CCN family member expression in cartilage neoplasia.
Growth plate chondrocytes undergo a coordinated differentiation process resulting in terminal differentiation and new bone… (More)
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Highly Cited
1999
Highly Cited
1999
The C-terminal domain of the regulatory protein NOVH is sufficient to promote interaction with fibulin 1C: a clue for a role of NOVH in cell-adhesion signaling.
The NOVH protein belongs to the emerging CCN [Connective tissue growth factor (CTGF), Cyr61/Cef10, nephroblastoma overexpressed… (More)
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