Skip to search formSkip to main contentSkip to account menu

Nelipepimut-S

Known as: L-Leucine, L-lysyl-L-isoleucyl-L-phenylalanylglycyl-L-seryl-L-leucyl-L-alanyl-L- phenylalanyl-, E75 Peptide, Human Receptor Tyrosine-Protein Kinase erbB-2 (Proto-Oncogene Neu, Tyrosine Kinase- type Cell Surface Receptor HER2, CD340)-(347-355)-Peptide 
A cancer vaccine comprised of a human leukocyte antigen (HLA) A2/A3 restricted HER2/neu (human epidermal growth factor receptor 2; ErbB2) nonapeptide… 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2017
Highly Cited
2017
Early-phase clinical trials evaluating CD8+ T cell-eliciting, HER2-derived peptide vaccines administered to HER2+ breast cancer… 
Review
2012
Review
2012
There is enthusiasm for using vaccines to stimulate the immune system to treat cancer. In this article, the authors review the… 
2011
2011
The authors are conducting clinical trials of the HER‐2/neu E75‐peptide vaccine in clinically disease‐free breast cancer (BC… 
Highly Cited
2009
Highly Cited
2009
Purpose: HER2/neu, a source of immunogenic peptides, is expressed in >75% of breast cancer patients. We have conducted clinical… 
Review
2008
Review
2008
E75 (HER2/neu 369–377) is an immunogenic peptide from the HER2/neu protein which is overexpressed in many breast cancer patients… 
Highly Cited
2007
Highly Cited
2007
We used the Luminex assay to compare serum cytokine profiles of breast cancer patients (BCa) to healthy controls, node-positive… 
Highly Cited
2006
Highly Cited
2006
E75 and GP2 are human leukocyte antigen (HLA)‐A2‐restricted immunogenic peptides derived from the HER2/neu protein. In a E75… 
2006
2006
Purpose: We studied serum monocyte chemotactic protein-1 (MCP-1) levels in breast cancer patients in relationship to their… 
Highly Cited
2004
Highly Cited
2004
A pilot vaccine study was conducted to test the safety and immunological efficacy of four monthly immunizations of an MHC class I… 
2004
2004
HER2/neu is a proto-oncogene and a member of the epidermal growth factor receptor family of proteins that is overexpressed in…