Nelipepimut-S

Known as: L-Leucine, L-lysyl-L-isoleucyl-L-phenylalanylglycyl-L-seryl-L-leucyl-L-alanyl-L- phenylalanyl-, E75 Peptide, Human Receptor Tyrosine-Protein Kinase erbB-2 (Proto-Oncogene Neu, Tyrosine Kinase- type Cell Surface Receptor HER2, CD340)-(347-355)-Peptide 
A cancer vaccine comprised of a human leukocyte antigen (HLA) A2/A3 restricted HER2/neu (human epidermal growth factor receptor 2; ErbB2) nonapeptide… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2003-2018
02420032018

Papers overview

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2017
2017
Early-phase clinical trials evaluating CD8+ T cell-eliciting, HER2-derived peptide vaccines administered to HER2+ breast cancer… (More)
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Review
2012
Review
2012
There is enthusiasm for using vaccines to stimulate the immune system to treat cancer. In this article, the authors review the… (More)
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2011
2011
BACKGROUND The authors are conducting clinical trials of the HER-2/neu E75-peptide vaccine in clinically disease-free breast… (More)
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2007
2007
We used the Luminex assay to compare serum cytokine profiles of breast cancer patients (BCa) to healthy controls, node-positive… (More)
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2007
2007
A vaccine designed to treat breast cancer has performed surprisingly well in an initial clinical study. In a phase II trial of… (More)
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2006
2006
BACKGROUND E75 and GP2 are human leukocyte antigen (HLA)-A2-restricted immunogenic peptides derived from the HER2/neu protein. In… (More)
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2006
2006
PURPOSE We studied serum monocyte chemotactic protein-1 (MCP-1) levels in breast cancer patients in relationship to their… (More)
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2006
2006
We are conducting clinical trials of the E75 peptide as a vaccine in breast cancer (BrCa) patients. We assessed T cell… (More)
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2004
2004
HER2/neu is a proto-oncogene and a member of the epidermal growth factor receptor family of proteins that is overexpressed in… (More)
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2003
2003
A pilot vaccine study was conducted to test the safety and immunological efficacy of four monthly immunizations of an MHC class I… (More)
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