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Negative Elongation Factor A Protein

Known as: NELF-A, Negative Elongation Factor A, Wolf-Hirschhorn Syndrome Candidate 2 Protein 
Negative elongation factor A (528 aa, ~57 kDa) is encoded by the human WHSC2 gene. This protein plays a role in transcriptional elongation.
National Institutes of Health

Papers overview

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2017
2017
While ecological adaptation in insects can be reflected by plasticity of phenotype, determining the causes and molecular… Expand
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2016
2016
Transcription regulation in metazoans often involves promoter-proximal pausing of RNA polymerase (Pol) II, which requires the 4… Expand
2016
2016
The association of DSIF and NELF with initiated RNA Polymerase II (Pol II) is the general mechanism for inducing promoter… Expand
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2014
2014
A gene induction competition assay has recently uncovered new inhibitory activities of two transcriptional cofactors, NELF-A and… Expand
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2013
2013
Background: Understanding glucocorticoid receptor (GR)-regulated gene transcription requires detailed description of cofactor… Expand
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2012
2012
Wolf-Hirschhorn syndrome (WHS) is a contiguous gene deletion disorder associated with the distal part of the short arm of… Expand
2012
2012
Background: Current descriptions of steroid hormone action are largely phenomenological rather than mechanistic. Results… Expand
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2011
2011
ABSTRACT Glycyrrhizic acid (GA), a derivative of licorice, selectively inhibits the growth of lymphocytes latently infected with… Expand
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Highly Cited
2009
Highly Cited
2009
The human negative elongation factor (NELF) is a four-subunit protein complex that inhibits the movement of RNA polymerase II… Expand
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Highly Cited
2003
Highly Cited
2003
ABSTRACT The multisubunit transcription elongation factor NELF (for negative elongation factor) acts together with DRB (5,6… Expand