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Narcolepsy

Known as: excessive uncontrollable daytime sleepiness, Gelineaus Syndrome, Narcolepsy NOS 
A condition characterized by recurrent episodes of daytime somnolence and lapses in consciousness (microsomnias) that may be associated with… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
Orexins, also known as hypocretins, are two neuropeptides secreted from orexin-containing neurons, mainly in the lateral… Expand
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Review
2018
Review
2018
Histamine has been one of the most studied substances in medicine, playing a major role in diverse (patho)physiological processes… Expand
Review
2018
Review
2018
The lateral hypothalamus is comprised of a heterogeneous mix of neurons that serve to integrate and regulate sleep, feeding… Expand
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Highly Cited
2001
Highly Cited
2001
Orexins (hypocretins) are a pair of neuropeptides implicated in energy homeostasis and arousal. Recent reports suggest that loss… Expand
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Highly Cited
2000
Highly Cited
2000
Alterations in the hypocretin receptor 2 and preprohypocretin genes produce narcolepsy in animal models. Hypocretin was… Expand
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Highly Cited
2000
Highly Cited
2000
Murine and canine narcolepsy can be caused by mutations of the hypocretin (Hcrt) (orexin) precursor or Hcrt receptor genes. In… Expand
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Highly Cited
2000
Highly Cited
2000
We explored the role of hypocretins in human narcolepsy through histopathology of six narcolepsy brains and mutation screening of… Expand
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Highly Cited
1999
Highly Cited
1999
Neurons containing the neuropeptide orexin (hypocretin) are located exclusively in the lateral hypothalamus and send axons to… Expand
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Highly Cited
1999
Highly Cited
1999
Narcolepsy is a disabling sleep disorder affecting humans and animals. It is characterized by daytime sleepiness, cataplexy, and… Expand
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Highly Cited
1991
Highly Cited
1991
The development and use of a new scale, the Epworth sleepiness scale (ESS), is described. This is a simple, self-administered… Expand
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