Narcolepsy

Known as: excessive uncontrollable daytime sleepiness, Gelineaus Syndrome, Narcolepsy NOS 
A condition characterized by recurrent episodes of daytime somnolence and lapses in consciousness (microsomnias) that may be associated with… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1936-2017
010020019362016

Papers overview

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Highly Cited
2003
Highly Cited
2003
Narcolepsy-cataplexy, a neurological disorder associated with the absence of hypothalamic orexin (hypocretin) neuropeptides… (More)
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Highly Cited
2002
Highly Cited
2002
CONTEXT Narcolepsy, a neurological disorder affecting 1 in 2000 individuals, is associated with HLA-DQB1*0602 and low… (More)
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Highly Cited
2001
Highly Cited
2001
Orexins (hypocretins) are a pair of neuropeptides implicated in energy homeostasis and arousal. Recent reports suggest that loss… (More)
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Highly Cited
2001
Highly Cited
2001
Human narcolepsy-cataplexy, a sleep disorder associated with a centrally mediated hypocretin (orexin) deficiency, is tightly… (More)
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Highly Cited
2000
Highly Cited
2000
Alterations in the hypocretin receptor 2 and preprohypocretin genes produce narcolepsy in animal models. Hypocretin was… (More)
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Highly Cited
2000
Highly Cited
2000
Murine and canine narcolepsy can be caused by mutations of the hypocretin (Hcrt) (orexin) precursor or Hcrt receptor genes. In… (More)
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Highly Cited
2000
Highly Cited
2000
We explored the role of hypocretins in human narcolepsy through histopathology of six narcolepsy brains and mutation screening of… (More)
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Highly Cited
1999
Highly Cited
1999
Neurons containing the neuropeptide orexin (hypocretin) are located exclusively in the lateral hypothalamus and send axons to… (More)
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Highly Cited
1999
Highly Cited
1999
Narcolepsy is a disabling sleep disorder affecting humans and animals. It is characterized by daytime sleepiness, cataplexy, and… (More)
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Highly Cited
1991
Highly Cited
1991
The development and use of a new scale, the Epworth sleepiness scale (ESS), is described. This is a simple, self-administered… (More)
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