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Narcolepsy
Known as:
excessive uncontrollable daytime sleepiness
, Gelineaus Syndrome
, Narcolepsy NOS
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A condition characterized by recurrent episodes of daytime somnolence and lapses in consciousness (microsomnias) that may be associated with…
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National Institutes of Health
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Related topics
Related topics
35 relations
24 HR Methylphenidate Hydrochloride 27 MG Extended Release Oral Tablet
24 HR Methylphenidate Hydrochloride 36 MG Extended Release Oral Tablet
24 HR Methylphenidate Hydrochloride 54 MG Extended Release Oral Tablet
30/70 Release 24 HR Methylphenidate Hydrochloride 10 MG Extended Release Oral Capsule [Metadate]
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Broader (4)
CNS disorder
Dyssomnias
Sleep Disorders
nervous system disorder
Narrower (2)
Irresistible sleepiness, cataplexy and onset of sleep in desynchronized phase
Narcolepsy-Cataplexy Syndrome
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2002
Highly Cited
2002
The role of cerebrospinal fluid hypocretin measurement in the diagnosis of narcolepsy and other hypersomnias.
E. Mignot
,
G. Lammers
,
+9 authors
S. Nishino
Archives of neurology
2002
Corpus ID: 1902623
CONTEXT Narcolepsy, a neurological disorder affecting 1 in 2000 individuals, is associated with HLA-DQB1*0602 and low…
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Highly Cited
2001
Highly Cited
2001
Genetic Ablation of Orexin Neurons in Mice Results in Narcolepsy, Hypophagia, and Obesity
J. Hara
,
C. Beuckmann
,
+8 authors
T. Sakurai
Neuron
2001
Corpus ID: 16735936
Highly Cited
2001
Highly Cited
2001
Complex HLA-DR and -DQ interactions confer risk of narcolepsy-cataplexy in three ethnic groups.
E. Mignot
,
L. Lin
,
+12 authors
N. Risch
American journal of human genetics
2001
Corpus ID: 15054694
Human narcolepsy-cataplexy, a sleep disorder associated with a centrally mediated hypocretin (orexin) deficiency, is tightly…
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Highly Cited
2000
Highly Cited
2000
A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains
C. Peyron
,
J. Faraco
,
+19 authors
E. Mignot
Nature Medicine
2000
Corpus ID: 18076282
We explored the role of hypocretins in human narcolepsy through histopathology of six narcolepsy brains and mutation screening of…
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Highly Cited
2000
Highly Cited
2000
Hypocretin (orexin) deficiency in human narcolepsy
S. Nishino
,
B. Ripley
,
S. Overeem
,
G. Lammers
,
E. Mignot
The Lancet
2000
Corpus ID: 43725707
Highly Cited
2000
Highly Cited
2000
Reduced Number of Hypocretin Neurons in Human Narcolepsy
T. Thannickal
,
R. Moore
,
+5 authors
J. Siegel
Neuron
2000
Corpus ID: 5961605
Highly Cited
1999
Highly Cited
1999
Narcolepsy in orexin Knockout Mice Molecular Genetics of Sleep Regulation
R. Chemelli
,
J. Willie
,
+12 authors
M. Yanagisawa
Cell
1999
Corpus ID: 89799178
Highly Cited
1999
Highly Cited
1999
The Sleep Disorder Canine Narcolepsy Is Caused by a Mutation in the Hypocretin (Orexin) Receptor 2 Gene
Ling Lin
,
J. Faraco
,
+7 authors
E. Mignot
Cell
1999
Corpus ID: 902666
Review
1998
Review
1998
Genetic and familial aspects of narcolepsy
E. Mignot
Neurology
1998
Corpus ID: 24213006
Narcolepsy-cataplexy is a disabling sleep disorder characterized by excessive daytime sleepiness and abnormal REM sleep. The…
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Highly Cited
1991
Highly Cited
1991
A new method for measuring daytime sleepiness: the Epworth sleepiness scale.
M. Johns
Sleep
1991
Corpus ID: 21863890
The development and use of a new scale, the Epworth sleepiness scale (ESS), is described. This is a simple, self-administered…
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