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NZW Mouse

Known as: NZW 
 
National Institutes of Health

Papers overview

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Highly Cited
2005
Highly Cited
2005
Specific inhibition of the mitochondrial permeability transition prevents lethal reperfusion injury.
The aim of the present study was to determine whether specific inhibition of mitochondrial permeability transition (MPT) by… Expand
Highly Cited
1999
Highly Cited
1999
Epistatic modifiers of autoimmunity in a murine model of lupus nephritis.
Sle1 and Sle3 are NZW-derived loci that mediate lupus nephritis on a C57BL/6 background. The absence of severe autoimmunity in… Expand
Highly Cited
1998
Highly Cited
1998
Uncoupling of immune complex formation and kidney damage in autoimmune glomerulonephritis.
The generation of autoantibody and subsequent tissue deposition of immune complexes (IC) is thought to trigger the pathogenic… Expand
Highly Cited
1994
Highly Cited
1994
Anticardiolipin antibodies recognize beta 2-glycoprotein I structure altered by interacting with an oxygen modified solid phase surface
Anticardiolipin antibodies (aCL) derived from the sera of individuals exhibiting the antiphospholipid syndrome (APS) directly… Expand
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Highly Cited
1994
Highly Cited
1994
Interleukin 6 promotes murine lupus in NZB/NZW F1 mice.
To investigate the role of IL-6 in systemic lupus erythematosus (SLE), we selectively inhibited IL-6 in lupus-prone NZB/NZW F1(B… Expand
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Highly Cited
1988
Highly Cited
1988
Tumour necrosis factor-α in murine autoimmune 'lupus' nephritis
The (NZB×NZW)F1 hybrid mouse develops a severe autoimmune disease similar to systemic lupus erythematosus in humans. Both the… Expand
Highly Cited
1985
Highly Cited
1985
Successful treatment of autoimmunity in NZB/NZW F1 mice with monoclonal antibody to L3T4
Autoimmune NZB/NZW mice were treated with weekly injections of monoclonal antibody (mAb) to L3T4, an antigen expressed on a… Expand
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Highly Cited
1981
Highly Cited
1981
Dietary enrichment with the polyunsaturated fatty acid eicosapentaenoic acid prevents proteinuria and prolongs survival in NZB x NZW F1 mice.
Prostaglandins and related compounds are active mediators of inflammation, but data concerning their role in the pathogenesis of… Expand
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Highly Cited
1980
Highly Cited
1980
Effects of thymectomy or androgen administration upon the autoimmune disease of MRL/Mp-lpr/lpr mice.
MRL/lpr and NZB X NZW F1 mice were neonatally thymectomized or treated with androgens from 2 weeks of age, and their natural… Expand
Highly Cited
1978
Highly Cited
1978
Effect of castration and sex hormone treatment on survival, anti- nucleic acid antibodies, and glomerulonephritis in NZB/NZW F1 mice
NZB/NZW F1 mice of both sexes were castrated at 2 wk of age and implanted subcutaneously with silastic tubes containing either 5… Expand
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