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NUDT5 gene

Known as: hYSAH1, NUCLEOSIDE DIPHOSPHATE-LINKED MOIETY X MOTIF 5, YSA1, S. CEREVISIAE, HOMOLOG OF 
National Institutes of Health

Related topics

Related topics

2 relations
NUDT6 geneNUDT8 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
The high expression of MTH1 and NUDT5 predict a poor survival and are associated with malignancy of esophageal squamous cell carcinoma
Background MTH1 and NUDT5 effectively degrade nucleotides containing 8-oxoguanine. MTH1 and NUDT5 have been linked to the… 
2019
2019
Expression of Oncogenic Drivers in 3D Cell Culture Depends on Nuclear ATP Synthesis by NUDT5
The growth of cancer cells as oncospheres in three-dimensional (3D) culture provides a robust cell model for understanding cancer… 
2018
2018
Hepatitis B Virus X Protein Increases 8-Oxo-7,8-Dihydro-2ʹ-Deoxyguanosine (8-Oxodg) Level via Repressing MTH1/ MTH2 Expression in Hepatocytes
Background/Aims: Chronic hepatitis B virus (HBV) infection markedly increases the risk of development of hepatocellular carcinoma… 
2017
2017
MutT-related proteins are novel progression and prognostic markers for colorectal cancer
Background MutT-related proteins, including MTH1, MTH2, MTH3 and NUDT5, can effectively degrade 8-oxoGua-containing nucleotides… 
2011
2011
Cleavage of oxidized guanine nucleotide and ADP sugar by human NUDT5 protein.
MutT-related proteins, including Escherichia coli MutT and the human MTH1 (NUDT1), degrade 8-oxo-7, 8-dihydrodeoxyguanosine… 
2011
2011
Diverse substrate recognition and hydrolysis mechanisms of human NUDT5
Human NUDT5 (hNUDT5) hydrolyzes various modified nucleoside diphosphates including 8-oxo-dGDP, 8-oxo-dADP and ADP-ribose (ADPR… 
2011
2011
NDX-1 protein hydrolyzes 8-oxo-7, 8-dihydrodeoxyguanosine-5'-diphosphate to sanitize oxidized nucleotides and prevent oxidative stress in Caenorhabditis elegans.
8-oxo-dGTP is generated in the nucleotide pool by direct oxidation of dGTP or phosphorylation of 8-oxo-dGDP. It can be… 
Highly Cited
2010
Highly Cited
2010
Suppression of mutagenesis by 8-hydroxy-2'-deoxyguanosine 5'-triphosphate (7,8-dihydro-8-oxo-2'-deoxyguanosine 5'-triphosphate) by human MTH1, MTH2, and NUDT5.
2009
2009
NUDT5 hydrolyzes oxidized deoxyribonucleoside diphosphates with broad substrate specificity.
Review
1999
Review
1999
The MutT motif family of nucleotide phosphohydrolases in man and human pathogens (review).
Human cells express at least eight members of the MutT motif protein (or nudix hydrolase) family. These enzymes are believed to… 
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