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NUDT15 gene

Known as: FLJ10956, MTH2, NUCLEOSIDE DIPHOSPHATE-LINKED MOIETY X MOTIF 15 
 
National Institutes of Health

Papers overview

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2017
2017
Prolonged exposure to thiopurines (eg, mercaptopurine [MP]) is essential for curative therapy in acute lymphoblastic leukemia… Expand
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2017
2017
Background: NUDT15 c.415C>T was a novel genetic marker confirmed in our center for thiopurine-induced leukopenia in Chinese… Expand
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2017
2017
Thiopurines [e.g. mercaptopurine (MP)] are widely used as chemotherapeutic agents in the treatment of pediatric acute… Expand
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2016
2016
A recent study identified a variant of the NUDT15 gene (rs116855232 C>T) associated with intolerance to thiopurine in Korean… Expand
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2016
2016
Thiopurines are a standard treatment for childhood leukemia, but like all chemotherapeutics, their use is limited by inherent or… Expand
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2016
2016
Acute lymphoblastic leukemia (ALL) is the most common hematologic malignancy in children[1][1]. Prolongation of therapy by… Expand
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Highly Cited
2015
Highly Cited
2015
Genotyping of TPMT prior to 6-mercaptopurine (6-MP) administration in acute lymphoblastic leukaemia (ALL) patients has been… Expand
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2015
2015
BackgroundNUDT15 R139C (rs116855232) is a recently identified genetic factor responsible for thiopurine-induced leukocytopenia… Expand
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2003
2003
In an effort to characterize further the patterns of selection and adaptive evolution at the methuselah locus in Drosophila… Expand
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Highly Cited
1999
Highly Cited
1999
Abstract The plantar pressure distribution during the push-off phase of walking was measured with the EMED-SF4 system of Novel… Expand
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