NUDT15 gene

Known as: FLJ10956, MTH2, NUCLEOSIDE DIPHOSPHATE-LINKED MOIETY X MOTIF 15 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1992-2017
024619922017

Papers overview

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2017
2017
Thiopurines [e.g. mercaptopurine (MP)] are widely used as chemotherapeutic agents in the treatment of pediatric acute… (More)
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2017
2017
Thiopurines are widely used as anticancer and immunosuppressive agents. However, life-threatening myelotoxicity has been noticed… (More)
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2016
2016
The pharmacokinetics among children has been altered dynamically. The difference between children and adults is caused by… (More)
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2015
2015
Genotyping of TPMT prior to 6-mercaptopurine (6-MP) administration in acute lymphoblastic leukaemia (ALL) patients has been… (More)
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2015
2015
NUDT15 R139C (rs116855232) is a recently identified genetic factor responsible for thiopurine-induced leukocytopenia and hair… (More)
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2012
2012
Most of the proteins carrying the 23-residue MutT-related sequence are capable of hydrolyzing compounds with a general structure… (More)
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2009
2009
Proliferating cell nuclear antigen (PCNA) has been demonstrated to interact with multiple proteins involved in several metabolic… (More)
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2003
2003
MutT-related proteins degrade 8-oxo-7,8-dihydrodeoxyguanosine triphosphate (8-oxo-dGTP), a mutagenic substrate for DNA synthesis… (More)
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1992
1992
By pulsed-field gel electrophoresis of chromosomal DNA and hybridization with a cloned MTH1 (CUP1) gene, we determined the… (More)
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