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NUAK2 gene
Known as:
NUAK FAMILY, SNF1-LIKE KINASE, 2
, SNF1/AMP activated protein kinase
, SNF1/AMPK-RELATED PROTEIN KINASE
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National Institutes of Health
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Papers overview
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Highly Cited
2018
Highly Cited
2018
NUAK2 is a critical YAP target in liver cancer
Wei-Chien Yuan
,
Brian J Pepe-Mooney
,
+7 authors
F. Camargo
Nature Communications
2018
Corpus ID: 53565965
The Hippo-YAP signaling pathway is a critical regulator of proliferation, apoptosis, and cell fate. The main downstream effector…
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Highly Cited
2017
Highly Cited
2017
WIPI3 and WIPI4 β-propellers are scaffolds for LKB1-AMPK-TSC signalling circuits in the control of autophagy
Daniela Bakula
,
A. Müller
,
+9 authors
T. Proikas-Cezanne
Nature communications
2017
Corpus ID: 7203044
Autophagy is controlled by AMPK and mTOR, both of which associate with ULK1 and control the production of phosphatidylinositol 3…
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Highly Cited
2014
Highly Cited
2014
Characterization of WZ4003 and HTH-01-015 as selective inhibitors of the LKB1-tumour-suppressor-activated NUAK kinases
Sourav Banerjee
,
S. Buhrlage
,
+7 authors
N. Gray
The Biochemical journal
2014
Corpus ID: 10134716
The related NUAK1 and NUAK2 are members of the AMPK (AMP-activated protein kinase) family of protein kinases that are activated…
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Review
2013
Review
2013
The regulation and function of the NUAK family.
Xianglan Sun
,
Ling Gao
,
H. Chien
,
Wan-Chun Li
,
Jiajun Zhao
Journal of molecular endocrinology
2013
Corpus ID: 6917189
AMP-activated protein kinase (AMPK) is a critical regulator of cellular and whole-body energy homeostasis. Twelve AMPK-related…
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2013
2013
Association between Phosphorylated AMP-Activated Protein Kinase and MAPK3/1 Expression and Prognosis for Patients with Gastric Cancer
Jong Gwang Kim
,
Soo Jung Lee
,
+6 authors
Su-jin Kim
Oncology
2013
Corpus ID: 207713018
Objectives: Phosphorylated AMP-activated protein kinase (pAMPK) plays a central role in cellular metabolic sensing and energy…
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2013
2013
The AMPK-related kinase SNARK regulates hepatitis C virus replication and pathogenesis through enhancement of TGF-β signaling.
Kaku Goto
,
Wenyu Lin
,
+8 authors
R. Chung
Journal of hepatology
2013
Corpus ID: 1890646
2011
2011
An association between NUAK2 and MRIP reveals a novel mechanism for regulation of actin stress fibers
T. Vallenius
,
Kari Vaahtomeri
,
Bianca Kovac
,
A. Osiceanu
,
M. Viljanen
,
T. Mäkelä
Journal of Cell Science
2011
Corpus ID: 207165784
Actin stress fiber assembly and contractility in nonmuscle motile cells requires phosphorylation of myosin regulatory light chain…
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Highly Cited
2010
Highly Cited
2010
New Roles for the LKB1-NUAK Pathway in Controlling Myosin Phosphatase Complexes and Cell Adhesion
A. Zagórska
,
M. Deák
,
+5 authors
D. Alessi
Science Signaling
2010
Corpus ID: 24688911
The kinase NUAK1, which is linked to tumor invasion, promotes cell detachment by activating cytoskeletal motor proteins. An LKB1…
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Review
2009
Review
2009
The regulation and function of mammalian AMPK‐related kinases
N. J. Bright
,
C. Thornton
,
D. Carling
Acta physiologica
2009
Corpus ID: 30849565
AMP‐activated protein kinase (AMPK) is a key regulator of cellular and whole‐body energy homeostasis. Recently, 12 AMPK‐related…
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Highly Cited
2004
Highly Cited
2004
LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR‐1
J. Lizcano
,
O. Göransson
,
+8 authors
D. Alessi
The EMBO journal
2004
Corpus ID: 30339778
We recently demonstrated that the LKB1 tumour suppressor kinase, in complex with the pseudokinase STRAD and the scaffolding…
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