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NUAK2 gene

Known as: NUAK FAMILY, SNF1-LIKE KINASE, 2, SNF1/AMP activated protein kinase, SNF1/AMPK-RELATED PROTEIN KINASE 
National Institutes of Health

Papers overview

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Highly Cited
2018
Highly Cited
2018
NUAK2 is a critical YAP target in liver cancer
The Hippo-YAP signaling pathway is a critical regulator of proliferation, apoptosis, and cell fate. The main downstream effector… 
Highly Cited
2017
Highly Cited
2017
WIPI3 and WIPI4 β-propellers are scaffolds for LKB1-AMPK-TSC signalling circuits in the control of autophagy
Autophagy is controlled by AMPK and mTOR, both of which associate with ULK1 and control the production of phosphatidylinositol 3… 
Highly Cited
2014
Highly Cited
2014
Characterization of WZ4003 and HTH-01-015 as selective inhibitors of the LKB1-tumour-suppressor-activated NUAK kinases
The related NUAK1 and NUAK2 are members of the AMPK (AMP-activated protein kinase) family of protein kinases that are activated… 
Review
2013
Review
2013
The regulation and function of the NUAK family.
AMP-activated protein kinase (AMPK) is a critical regulator of cellular and whole-body energy homeostasis. Twelve AMPK-related… 
2013
2013
Association between Phosphorylated AMP-Activated Protein Kinase and MAPK3/1 Expression and Prognosis for Patients with Gastric Cancer
Objectives: Phosphorylated AMP-activated protein kinase (pAMPK) plays a central role in cellular metabolic sensing and energy… 
2013
2013
The AMPK-related kinase SNARK regulates hepatitis C virus replication and pathogenesis through enhancement of TGF-β signaling.
2011
2011
An association between NUAK2 and MRIP reveals a novel mechanism for regulation of actin stress fibers
Actin stress fiber assembly and contractility in nonmuscle motile cells requires phosphorylation of myosin regulatory light chain… 
Highly Cited
2010
Highly Cited
2010
New Roles for the LKB1-NUAK Pathway in Controlling Myosin Phosphatase Complexes and Cell Adhesion
The kinase NUAK1, which is linked to tumor invasion, promotes cell detachment by activating cytoskeletal motor proteins. An LKB1… 
Review
2009
Review
2009
The regulation and function of mammalian AMPK‐related kinases
AMP‐activated protein kinase (AMPK) is a key regulator of cellular and whole‐body energy homeostasis. Recently, 12 AMPK‐related… 
Highly Cited
2004
Highly Cited
2004
LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR‐1
We recently demonstrated that the LKB1 tumour suppressor kinase, in complex with the pseudokinase STRAD and the scaffolding… 
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