NUAK1 gene

Known as: NuaK1, ARK5, NUAK family kinase 1 
This gene plays a role in DNA damage response, apoptosis inhibition, cell adhesion, cellular senescence, and cell proliferation.
National Institutes of Health

Topic mentions per year

Topic mentions per year

2004-2018
05101520042018

Papers overview

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2014
2014
Background:Lung cancer is a leading cause of cancer-related mortality worldwide and non-small-cell lung carcinoma (NSCLC) is… (More)
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2014
2014
Melanoma is one of the deadliest human cancers, responsible for approximately 80% of skin cancer mortalities. The aggressiveness… (More)
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2014
2014
microRNA-96 (miR-96) is known to be downregulated in pancreatic cancer. The overexpression of miR-96 in MIA PaCa-2 pancreatic… (More)
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Highly Cited
2013
Highly Cited
2013
The molecular mechanisms underlying the axon arborization of mammalian neurons are poorly understood but are critical for the… (More)
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2011
2011
It has been suggested that adenosine monophosphate-activated protein kinase (AMPK) and 12 AMPK-related kinases (ARK), including… (More)
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2010
2010
The AMPK-related kinases NUAK1 and NUAK2 are activated by the tumor suppressor LKB1. We found that NUAK1 interacts with several… (More)
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2010
2010
Senescence is an irreversible cell-cycle arrest that is elicited by a wide range of factors, including replicative exhaustion… (More)
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Highly Cited
2008
Highly Cited
2008
AMPK (AMP-activated protein kinase)-related kinases regulate cell polarity as well as proliferation and are activated by the LKB1… (More)
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2004
Highly Cited
2004
We recently demonstrated that the LKB1 tumour suppressor kinase, in complex with the pseudokinase STRAD and the scaffolding… (More)
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2004
2004
A novel member of the human AMPK family, ARK5, was recently discovered to be a key molecule in mediating cancer cell migration… (More)
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