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ABSTRACT During the development of the central nervous system (CNS), only motor axons project into peripheral nerves. Little is… Expand The vestibular system of the inner ear detects head position using three orthogonally oriented semicircular canals; even slight… Expand Netrin 1 was initially identified as an axon guidance factor, and recent studies indicate that it inhibits chemokine-directed… Expand Blood-brain barrier function is driven by the influence of astrocyte-secreted factors. During neuroinflammatory responses the… Expand The establishment of anatomically stereotyped axonal projections is fundamental to neuronal function. While most neurons project… Expand BACKGROUND & AIMS
Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancers. It is characterized by substantial… Expand Molecular cues, such as netrin 1, guide axons by influencing growth cone motility. Rho GTPases are a family of intracellular… Expand Dorsal root ganglion (DRG) neurons extend axons to specific targets in the gray matter of the spinal cord. During development… Expand During embryonic development, tangentially migrating precerebellar neurons emit a leading process and then translocate their… Expand In spinal cord, oligodendrocyte precursors that give rise to myelin-forming cells originate in a restricted domain of the ventral… Expand