NOTUM gene

Known as: NOTUM, [Wnt protein] O-palmitoleoyl-L-serine hydrolase, NOTUM, DROSOPHILA, HOMOLOG OF 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1972-2017
024619722017

Papers overview

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2015
2015
Signalling by Wnt proteins is finely balanced to ensure normal development and tissue homeostasis while avoiding diseases such as… (More)
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2015
2015
Secreted Wnt morphogens are essential for embryogenesis and homeostasis and require a lipid/palmitoleoylate modification for… (More)
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2015
2015
Mechanisms determining final organ size are poorly understood. Animals undergoing regeneration or ongoing adult growth are likely… (More)
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2015
2015
The connection between colorectal cancer (CRC) and Wnt signaling pathway activation is well known, but full elucidation of the… (More)
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2013
2013
Animals establish their body plans in embryogenesis, but only a few animals can recapitulate this signaling milieu for… (More)
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2012
2012
Multiple developmental processes require tightly controlled Wnt signaling, and its misregulation leads to congenital… (More)
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Highly Cited
2008
Highly Cited
2008
Glypicans are heparan sulfate proteoglycans that are attached to the cell surface by a GPI (glycosylphosphatidylinositol)anchor… (More)
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2008
2008
The Drosophila Notum gene, which is regulated by the Wingless pathway, encodes a secreted hydrolase that modifies heparan sulfate… (More)
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Highly Cited
2005
Highly Cited
2005
Drosophila Wingless (Wg) is the founding member of the Wnt family of secreted proteins. During the wing development, Wg acts as a… (More)
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Highly Cited
2004
Highly Cited
2004
The glypican family of heparan sulfate proteoglycans has been implicated in formation of morphogen gradients. Here, we examine… (More)
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