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NOS3 gene

Known as: NITRIC OXIDE SYNTHASE, ENDOTHELIAL, ECNOS, Nitric Oxide Synthase 3 (Endothelial Cell) Gene 
This gene plays a role in signal transduction, angiogenesis and platelet aggregation.
National Institutes of Health

Related topics

Related topics

9 relations
Alzheimer's DiseaseAngiogenic ProcessHypertensive diseaseMuscle Contraction

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NOS3 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
Influence of eNOS haplotypes on the plasma nitric oxide products concentrations in hypertensive and type 2 diabetes mellitus patients.
Highly Cited
2007
Highly Cited
2007
Lack of endothelial nitric oxide synthase promotes endothelin-induced hypertension: lessons from endothelin-1 transgenic/endothelial nitric oxide synthase knockout mice.
Endothelin-1 (ET-1) is one of the most potent biologic vasoconstrictors. Nevertheless, transgenic mice that overexpress ET-1… 
Highly Cited
2006
Highly Cited
2006
Alteration of Decreased Plasma NO Metabolites and Platelet NO Synthase Activity by Paroxetine in Depressed Patients
Although major depression (MD) and cardiovascular disease (CVD) have been conclusively linked in the literature, the mechanism… 
Highly Cited
2003
Highly Cited
2003
C-reactive protein and atherothrombosis—Beyond a biomarker: an actual partaker of lesion formation
atherosclerosis and its complications represent the most common cause of death in Western societies. Over the past few years we… 
Highly Cited
2001
Highly Cited
2001
Sphingosine 1-Phosphate and Isoform-specific Activation of Phosphoinositide 3-Kinase β
Sphingosine 1-phosphate (S1P) is a platelet-derived sphingolipid that elicits diverse biological responses, including… 
Highly Cited
2001
Highly Cited
2001
Dynamic regulation of metabolism and respiration by endogenously produced nitric oxide protects against oxidative stress
One of the many biological functions of nitric oxide is the ability to protect cells from oxidative stress. To investigate the… 
Highly Cited
2000
Highly Cited
2000
Myocardial glucose uptake is regulated by nitric oxide via endothelial nitric oxide synthase in Langendorff mouse heart.
Although the role of nitric oxide (NO) in the modulation of vascular tone has been studied and well understood, its potential… 
Highly Cited
2000
Highly Cited
2000
Superoxide Production and Reactive Oxygen Species Signaling by Endothelial Nitric-oxide Synthase*
Reactive oxygen species can function as intracellular messengers, but linking these signaling events with specific enzymes has… 
Highly Cited
1998
Highly Cited
1998
New approaches to prevention and treatment of radial artery graft vasospasm.
BACKGROUND There has been renewed interest in radial artery (RA) conduits for coronary artery bypass because of the relative… 
Highly Cited
1996
Highly Cited
1996
Endothelial constitutive nitric oxide synthase protein and mRNA increased in rabbit atherosclerotic aorta despite impaired endothelium-dependent vascular relaxation.
Atherosclerotic arteries are well known to exhibit impaired endothelium-dependent relaxation (EDR), but the exact mechanism of… 
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