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NOS3 gene
Known as:
NITRIC OXIDE SYNTHASE, ENDOTHELIAL
, ECNOS
, Nitric Oxide Synthase 3 (Endothelial Cell) Gene
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This gene plays a role in signal transduction, angiogenesis and platelet aggregation.
National Institutes of Health
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Related topics
Related topics
9 relations
Alzheimer's Disease
Angiogenic Process
Hypertensive disease
Muscle Contraction
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NOS3 wt Allele
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2005
Highly Cited
2005
Calorie Restriction Promotes Mitochondrial Biogenesis by Inducing the Expression of eNOS
E. Nisoli
,
C. Tonello
,
+9 authors
M. Carruba
Science
2005
Corpus ID: 45482933
Calorie restriction extends life span in organisms ranging from yeast to mammals. Here, we report that calorie restriction for…
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Highly Cited
2002
Highly Cited
2002
A Self-Fulfilling Prophecy: C-Reactive Protein Attenuates Nitric Oxide Production and Inhibits Angiogenesis
S. Verma
,
Chao-Hung Wang
,
+8 authors
D. Stewart
Circulation
2002
Corpus ID: 6808584
Background—Given the central importance of nitric oxide (NO) in the development and clinical course of cardiovascular diseases…
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Highly Cited
2002
Highly Cited
2002
Endothelial Cell Senescence in Human Atherosclerosis: Role of Telomere in Endothelial Dysfunction
T. Minamino
,
H. Miyauchi
,
Toshihiko Yoshida
,
Y. Ishida
,
H. Yoshida
,
I. Komuro
Circulation
2002
Corpus ID: 16954970
Background—The functional changes associated with cellular senescence may be involved in human aging and age-related vascular…
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Highly Cited
2001
Highly Cited
2001
Caveolin-1 null mice are viable but show evidence of hyperproliferative and vascular abnormalities.
B. Razani
,
Jeffery A. Engelman
,
+14 authors
M. Lisanti
Journal of Biological Chemistry
2001
Corpus ID: 34804607
Caveolin-1 is the principal structural protein of caveolae membranes in fibroblasts and endothelia. Recently, we have shown that…
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Highly Cited
2000
Highly Cited
2000
Interaction of oestrogen receptor with the regulatory subunit of phosphatidylinositol-3-OH kinase
T. Simoncini
,
A. Hafezi-Moghadam
,
D. Brazil
,
K. Ley
,
W. Chin
,
J. Liao
Nature
2000
Corpus ID: 4329703
Oestrogen produces diverse biological effects through binding to the oestrogen receptor (ER). The ER is a steroid hormone nuclear…
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Highly Cited
1999
Highly Cited
1999
Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation
S. Dimmeler
,
I. Fleming
,
B. Fisslthaler
,
Corinna Hermann
,
R. Busse
,
A. Zeiher
Nature
1999
Corpus ID: 4409727
Nitric oxide (NO) produced by the endothelial NO synthase (eNOS) is a fundamental determinant of cardiovascular homesotasis: it…
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Highly Cited
1999
Highly Cited
1999
Regulation of endothelium-derived nitric oxide production by the protein kinase Akt
D. Fulton
,
J. Gratton
,
+6 authors
W. Sessa
Nature
1999
Corpus ID: 4394717
Endothelial nitric oxide synthase (eNOS) is the nitric oxide synthase isoform responsible for maintaining systemic blood pressure…
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Highly Cited
1998
Highly Cited
1998
Nitric oxide synthase modulates angiogenesis in response to tissue ischemia.
T. Murohara
,
T. Asahara
,
+10 authors
J. Isner
Journal of Clinical Investigation
1998
Corpus ID: 2823297
We tested the hypothesis that endothelial nitric oxide synthase (eNOS) modulates angiogenesis in two animal models in which…
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Highly Cited
1998
Highly Cited
1998
Dynamic activation of endothelial nitric oxide synthase by Hsp90
G. Garcı́a-Cardeña
,
R. Fan
,
+4 authors
W. Sessa
Nature
1998
Corpus ID: 4314484
Heat-shock protein 90 (Hsp90) coordinates the trafficking and regulation of diverse signalling proteins, but its precise role in…
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Highly Cited
1998
Highly Cited
1998
Post-transcriptional Regulation of Endothelial Nitric Oxide Synthase mRNA Stability by Rho GTPase*
U. Laufs
,
J. Liao
Journal of Biological Chemistry
1998
Corpus ID: 8877205
The mechanism by which 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase inhibitors increase endothelial nitric oxide synthase (eNOS…
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