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NMNAT1 gene

Known as: PYRIDINE NUCLEOTIDE ADENYLYLTRANSFERASE 1, NMNAT, PNAT1 
 
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
NAD metabolism regulates diverse biological processes, including ageing, circadian rhythm and axon survival. Axons depend on the… Expand
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Highly Cited
2012
Highly Cited
2012
Leber congenital amaurosis (LCA) is an infantile-onset form of inherited retinal degeneration characterized by severe vision loss… Expand
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Highly Cited
2012
Highly Cited
2012
Axons damaged by acute injury, toxic insults, or during neurodegenerative diseases undergo Wallerian or Wallerian-like… Expand
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Highly Cited
2012
Highly Cited
2012
The discovery of sirtuins (SIRT), a family of nicotinamide adenine dinucleotide (NAD)-dependent deacetylases, has indicated that… Expand
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Highly Cited
2010
Highly Cited
2010
Axon and synapse degeneration are common components of many neurodegenerative diseases, and their rescue is essential for… Expand
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Highly Cited
2009
Highly Cited
2009
Axonal degeneration is a key component of a variety of neurological diseases. Studies using wlds mutant mice have demonstrated… Expand
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Highly Cited
2009
Highly Cited
2009
Axonal degeneration is a hallmark of many neurological disorders. Studies in animal models of neurodegenerative diseases indicate… Expand
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Highly Cited
2008
Highly Cited
2008
Axonal degeneration is a prominent feature of many neurological disorders that are associated with mitochondrial dysfunction… Expand
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Highly Cited
2006
Highly Cited
2006
Wallerian degeneration refers to a loss of the distal part of an axon after nerve injury. Wallerian degeneration slow (Wlds) mice… Expand
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Highly Cited
2005
Highly Cited
2005
Nicotinamide mononucleotide adenylyltransferase (NMNAT) is the central enzyme of the NAD biosynthetic pathway. Three human NMNAT… Expand
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