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NK314

National Institutes of Health

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Broader (1)

Phenanthrenes

Papers overview

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2011
2011
DNA-Dependent Protein Kinase and Ataxia Telangiectasia Mutated (ATM) Promote Cell Survival in Response to NK314, a Topoisomerase IIα Inhibitor
4-Hydroxy-5-methoxy-2,3-dihydro-1H-[1,3]benzodioxolo[5,6-c]pyrrolo[1,2-f]-phenanthridium chloride (NK314) is a benzo[c… 
2008
2008
Isoform α Specifically Targets the NK 314 , a Topoisomerase II Inhibitor That and Chromosome Dynamics : DNA : Replication , Repair
2008
2008
The mechanism of action of a novel benzo[c]phenanthridine alkaloid, NK314 and the cellular responses
2007
2007
Inhibition of topoisomerase IIα and G2 cell cycle arrest by NK314, a novel benzo[c]phenanthridine currently in clinical trials
NK314 is a novel synthetic benzo[c]phenanthridine alkaloid that has recently entered clinical trials as an antitumor compound… 
2006
2006
NK314, a novel antitumor agent, induces rapid double strand DNA breaks by specific inhibition of topoisomerase IIα.
Proc Amer Assoc Cancer Res, Volume 47, 2006 5525 Background: NK314 is a synthetic benzo[c]phenanthridine analog and exhibits… 
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