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NK314

 
National Institutes of Health

Papers overview

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2019
2019
Etoposide (VP-16) is the topoisomerase 2 (Top2) inhibitor used for treating of glioma patients however at high dose with serious… Expand
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2019
2019
Topoisomerase II (Topo2) inhibitors in combination with cisplatin represent a common treatment modality used for glioma patients… Expand
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2011
2011
Adult T-cell leukemia-lymphoma (ATL) is an aggressive disease, incurable by standard chemotherapy. NK314, a new anticancer agent… Expand
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2011
2011
4-Hydroxy-5-methoxy-2,3-dihydro-1H-[1,3]benzodioxolo[5,6-c]pyrrolo[1,2-f]-phenanthridium chloride (NK314) is a benzo[c… Expand
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2011
2011
1Department of Internal Medicine, Faculty of Medicine, Saga University, Saga, Japan; 2Department of Genetic Medicine and… Expand
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Highly Cited
2008
Highly Cited
2008
Topoisomerase II (Top2) is a ubiquitous nuclear enzyme that relieves torsional stress in chromosomal DNA during various cellular… Expand
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2008
2008
NK314 is a novel synthetic benzo[c]phenanthridine alkaloid that shows strong antitumor activity. It inhibited topoisomerase II… Expand
2007
2007
NK314 is a novel synthetic benzo[c]phenanthridine alkaloid that has recently entered clinical trials as an antitumor compound… Expand
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2006
2006
Proc Amer Assoc Cancer Res, Volume 47, 2006 5525 Background: NK314 is a synthetic benzo[c]phenanthridine analog and exhibits… Expand