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To improve the outcome of cancer chemotherapy, strategies to enhance the efficacy of anticancer drugs are required. Sorafenib is… Expand Development of an effective low-cost anti-acquired immunodeficiency syndrome (AIDS) drugs is needed for treatment of AIDS… Expand Aim: NIK‐333 (an acyclic retinoid) has been reported to prevent recurrence of hepatocellular carcinoma (HCC) in patients after… Expand The effect of an acyclic synthetic retinoid analogue NIK-333, on the restoration of liver mass and recovery of liver function… Expand BACKGROUND & AIMS
We previously reported that impaired retinoid signaling in the liver causes steatohepatitis and hepatocellular… Expand BACKGROUND
In an attempt to develop effective and non-cytotoxic cancer chemopreventive derivatives of retinoids, a novel acyclic… Expand The mechanisms of prevention of the development of liver cancer by NIK-333, an acyclic retinoid (ACR), were investigated. The… Expand Adult T-cell leukemia (ATL) is caused by human T-cell leukemia virus type I (HTLV-I) and remains incurable. NIK-333, a novel… Expand Abstract: We investigated the preventive effects of a synthetic acyclic retinoid, NIK-333, on the early and late events of… Expand The present study was designed to determine the effects of NIK-333, a synthetic acyclic retinoid, on N-diethylnitrosamine (DEN… Expand