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NEUROG3 gene

Known as: NEUROGENIN 3, bHLHa7, NEUROG3 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
A novel NEUROG3 mutation in neonatal diabetes associated with a neuro‐intestinal syndrome
Neonatal diabetes mellitus (NDM) is a rare form of non‐autoimmune diabetes usually diagnosed in the first 6 months of life… 
2016
2016
A combination of cytokines EGF and CNTF protects the functional beta cell mass in mice with short-term hyperglycaemia
Aims/hypothesisWhen the beta cell mass or function declines beyond a critical point, hyperglycaemia arises. Little is known about… 
2015
2015
Epigenetic mechanisms of peptidergic regulation of gene expression during aging of human cells
Expression levels of genes encoding specific transcription factors and other functionally important proteins vary upon aging of… 
2015
2015
Differentiation of human-induced pluripotent stem cells into insulin-producing clusters.
OBJECTIVES In diabetes mellitus type 1, beta cells are mostly destroyed; while in diabetes mellitus type 2, beta cells are… 
2012
2012
Islet microarchitecture and glucose transporter expression of the pancreas of the marmoset monkey display similarities to the human
The common marmoset New World monkey (Callithrix jacchus), is a primate model with great potential for scientific research… 
2012
2012
Combined treatment with a dipeptidyl peptidase‐IV inhibitor (sitagliptin) and an angiotensin II type 1 receptor blocker (losartan) promotes islet regeneration via enhanced differentiation of…
Aim: The existence of pancreatic progenitor cells (PPCs) with differentiation capacity in the adult pancreas has rendered that… 
2009
2009
Gene therapy with neurogenin 3 and betacellulin reverses major metabolic problems in insulin-deficient diabetic mice.
Insulin deficiency in type 1 diabetes leads to disruptions in glucose, lipid, and ketone metabolism with resultant hyperglycemia… 
2008
2008
Combined expression of transcription factors induces AR42J-B13 cells to differentiate into insulin-producing cells.
Neurogenin 3 (Ngn3) is a transcription factor that regulates an initial step of differentiation from uncommitted pancreatic… 
2004
2004
Generation of monoclonal antibodies against mouse neurogenin 3: a new immunocytochemical tool to study the pancreatic endocrine progenitor cell.
The induction of pancreatic endocrine differentiation from undifferentiated precursor cells is a multi-step process regulated by… 
2001
2001
Mutations in the coding region of the neurogenin 3 gene (NEUROG3) are not a common cause of maturity-onset diabetes of the young in Japanese subjects.
Mutations in transcription factors that play a role in the development of the endocrine pancreas, such as insulin promoter factor… 
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