Skip to search formSkip to main contentSkip to account menu

NEDD8-specific protease activity

Known as: deneddylase activity 
Catalysis of the hydrolysis of NEDD8, a small ubiquitin-related modifier, from previously neddylated substrates. [GOC:mah]
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Deneddylase 1 regulates deneddylase activity of the Cop9 signalosome in Drosophila melanogaster
NEDD8 conjugation of Cullin has an important role in ubiquitin‐mediated protein degradation. The COP9 signalosome, of which CSN5… 
2015
2015
Integration of the catalytic subunit activates deneddylase activity in vivo as final step in fungal COP9 signalosome assembly
The eight‐subunit COP9 signalosome (CSN) is conserved from filamentous fungi to humans and functions at the interface between… 
2015
2015
COP9-Signalosome deneddylase activity is enhanced by simultaneous neddylation: insights into the regulation of an enzymatic protein complex
Cullin-RING ubiquitin ligases (CRLs) are regulated by neddylation, which is a post translation modification of the Cullin family… 
Review
2015
Review
2015
Studies on early cellular responses during Epstein-Barr virus infection
The human gamma-herpesvirus Epstein-Barr virus (EBV) has been implicated in the pathogenesis of a broad spectrum of lymphoid and… 
2009
2009
Tips A time-resolved fluorescence resonance energy transfer-based assay for DEN 1 peptidase activity
Neural precursor cell expressed, developmentally down-regulated gene 8 (NEDD8) is a recently discovered ubiquitin-like… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)