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NCOA4/RET Fusion Gene

Known as: RET/NCOA4 Oncogene, RET/PTC3, PTC3 CHIMERIC ONCOGENE 
A fusion gene that results from a paracentric inversion inv(10)(q11q11) which fuses the 5' portion of the NCOA4 gene and the 3' portion of the RET… 
National Institutes of Health

Related topics

Related topics

17 relations
Columnar Cell Variant Thyroid Gland Papillary CarcinomaCribriform-Morular Variant Thyroid Gland Papillary CarcinomaEncapsulated Follicular Variant Thyroid Gland Papillary CarcinomaFollicular Variant Thyroid Gland Papillary Carcinoma

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2016
Highly Cited
2016
Molecular Characterization of Sporadic Pediatric Thyroid Carcinoma with the DNA/RNA ThyroSeq v2 Next-Generation Sequencing Assay
The aim of this study was to test the hypothesis that our 60-gene DNA/RNA ThyroSeq v2 next-generation sequence (NGS) assay would… 
2016
2016
Radiation exposure, young age, and female gender are associated with high prevalence of RET/PTC1 and RET/PTC3 in papillary thyroid cancer: a meta-analysis
Background RET/PTC rearrangements have been identified as a specific genetic event in papillary thyroid cancer (PTC). We… 
Highly Cited
2006
Highly Cited
2006
Prevalence of RET/PTC rearrangements in thyroid papillary carcinomas: effects of the detection methods and genetic heterogeneity.
CONTEXT RET/PTC rearrangements have been reported in papillary thyroid carcinomas with variable frequency in studies that used… 
Highly Cited
2005
Highly Cited
2005
RET gene rearrangements (RET/PTC1 and RET/PTC3) in papillary thyroid carcinomas from an iodine‐rich country (Japan)
The frequency of RET rearrangements (RET/PTC) in papillary thyroid carcinomas varies significantly according to geographic area… 
2005
2005
Low prevalence of RET rearrangements (RET/PTC1, RET/PTC2, RET/PTC3, and ELKS-RET) in sporadic papillary thyroid carcinomas in Taiwan Chinese.
Somatic rearrangement of the tyrosine kinase receptor RET is restricted to papillary thyroid carcinoma (PTC). The prevalence of… 
Highly Cited
2004
Highly Cited
2004
Real-time quantitative RT-PCR identifies distinct c-RET, RET/PTC1 and RET/PTC3 expression patterns in papillary thyroid carcinoma
RET/PTC1 and RET/PTC3 are the markers for papillary thyroid carcinoma. Their reported prevalence varies broadly. Nonrearranged c… 
Highly Cited
2002
Highly Cited
2002
Assessment of RET/PTC oncogene activation and clonality in thyroid nodules with incomplete morphological evidence of papillary carcinoma: a search for the early precursors of papillary cancer.
2001
2001
Evaluation of combustion by-products of MTBE as a component of reformulated gasoline.
Highly Cited
2000
Highly Cited
2000
RET receptor expression in thyroid follicular epithelial cell-derived tumors.
The RET proto-oncogene encodes a receptor tyrosine kinase for transforming growth factor-beta-related neurotrophic factors, which… 
Highly Cited
1997
Highly Cited
1997
Comparison of the breakpoint regions of ELE1 and RET genes involved in the generation of RET/PTC3 oncogene in sporadic and in radiation-associated papillary thyroid carcinomas.
The RET/PTC3 oncogene is an activated form of the RET protooncogene, which is frequently rearranged in papillary thyroid… 
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