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NAPHTHOQUINE

National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Metabolite identification of the antimalarial naphthoquine using liquid chromatography-tandem high-resolution mass spectrometry in combination with multiple data-mining tools.
Naphthoquine (NQ) is one of important partner drugs of artemisinin-based combination therapy (ACT), which is recommended for the… 
2017
2017
Synthesis and in vivo antimalarial activity of novel naphthoquine derivatives with linear/cyclic structured pendants.
AIM Naphthoquine (NQ) was discovered by our institute as an antimalarial candidate in 1980s, and currently employed as an… 
2016
2016
Naphthoquine-induced Central Nervous System and Hepatic Vasculocentric Toxicity in the Beagle Dog
Naphthoquine phosphate (NP) was considered as a partner drug with a promising antimalarial drug candidate. Here we report… 
2014
2014
Artemisinin-naphthoquine versus Artemether-lumefantrine for treating uncomplicated plasmodium falciparum malaria in children: A randomized controlled trial of efficacy and safety
Introduction : Artemether-lumefantrine (AL), the most frequently prescribed ACTs for uncomplicated P. falciparum malaria… 
2012
2012
A pharmacokinetic approach to assess artemisinin–naphthoquine combination therapy for uncomplicated pediatric malaria
Evaluation of: Batty KT, Salman S, Moore BR et al. Artemisinin–naphthoquine combination therapy for uncomplicated pediatric… 
2011
2011
In vitro response of Plasmodium falciparum to naphthoquine combined with azithromycin
Objective To examine the in vitro response of naphthoquine-sensitive Plasmodium falciparum and naphthoquine-resistant P… 
2010
2010
In vitro sensitivity of Plasmodium falciparum to conventional and novel antimalarial drugs in Papua New Guinea
Objective  Recent clinical studies have shown high rates of malaria treatment failure in endemic areas of Papua New Guinea (PNG… 
2003
2003
[Efficacy of naphthoquine, artemisinine and a combination of the two drugs in the treatment of falciparum malaria].
OBJECTIVE To compare the efficacy and safety of naphthoquine, artemisinine and a combination of the two drugs in the treatment of… 
2002
2002
[Therapeutic effect of dihydroartemisinin combined with naphthoquine phosphate in patients with falciparum malaria].
OBJECTIVE To observe the therapeutic efficacy of dihydroartemisinin combined with naphthoquine phosphate in patients with… 
2001
2001
Observation on the effect of naphthoquine phosphate on the control of malaria in Qiongzhong County, Hainan Province
Objective To evaluate the effect of naphthoquine phosphate massively administered in a relative- ly large areas for the control… 
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