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NAI-107

 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

microbisporicin

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Two Flavoenzymes Catalyze the Post-Translational Generation of 5-Chlorotryptophan and 2-Aminovinyl-Cysteine during NAI-107 Biosynthesis.
Lantibiotics are ribosomally synthesized and post-translationally modified antimicrobial peptides containing thioether rings. In… Expand
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2016
2016
Structure and tRNA Specificity of MibB, a Lantibiotic Dehydratase from Actinobacteria Involved in NAI-107 Biosynthesis.
Class I lantibiotic dehydratases dehydrate selected Ser/Thr residues of a precursor peptide. Recent studies demonstrated the… Expand
2016
2016
Distinct mechanisms contribute to immunity in the lantibiotic NAI-107 producer strain Microbispora ATCC PTA-5024.
The investigation of self-resistance in antibiotic producers is important to understand the emergence of antibiotic resistance in… Expand
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2016
2016
The Lantibiotic NAI-107 Efficiently Rescues Drosophila melanogaster from Infection with Methicillin-Resistant Staphylococcus aureus USA300
ABSTRACT We used the fruit fly Drosophila melanogaster as a cost-effective in vivo model to evaluate the efficacy of novel… Expand
2015
2015
Brominated Variant of the Lantibiotic NAI-107 with Enhanced Antibacterial Potency.
We identified an Actinoallomurus strain producing NAI-107, a chlorinated lantibiotic effective against multidrug-resistant Gram… Expand
Highly Cited
2014
Highly Cited
2014
The Lantibiotic NAI-107 Binds to Bactoprenol-bound Cell Wall Precursors and Impairs Membrane Functions*
Background: NAI-107 is a potent lantibiotic with an unknown mode of action. Results: NAI-107 targets bactoprenol-bound cell… Expand
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2014
2014
Characterization of the congeners in the lantibiotic NAI-107 complex.
NAI-107, a lantibiotic produced by Microbispora sp. 107891, shows potent activity against multi-drug-resistant bacterial… Expand
2014
2014
In Vivo Pharmacokinetics and Pharmacodynamics of the Lantibiotic NAI-107 in a Neutropenic Murine Thigh Infection Model
ABSTRACT NAI-107 is a novel lantibiotic compound with potent in vitro activity against Gram-positive bacteria, including… Expand
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2012
2012
Solution structure by nuclear magnetic resonance of the two lantibiotics 97518 and NAI‐107
Lantibiotics 97518 and NAI‐107, produced by the related genera Planomonospora and Microbispora respectively, are members of a… Expand
Highly Cited
2011
Highly Cited
2011
Efficacy of the New Lantibiotic NAI-107 in Experimental Infections Induced by Multidrug-Resistant Gram-Positive Pathogens
ABSTRACT NAI-107 is a novel lantibiotic active against Gram-positive bacteria, including methicillin-resistant Staphylococcus… Expand
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