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NADP-Dependent Malic Enzyme

Known as: Malate Dehydrogenase, Malic Enzyme 1, EC 1.1.1.40 
NADP-dependent malic enzyme (572 aa, ~64 kDa) is encoded by the human ME1 gene. This protein plays a role in the oxidative decarboxylation of malate.
National Institutes of Health

Related topics

Related topics

13 relations
Carbohydrate MetabolismCytoplasmEnzyme GeneLipid Metabolism

Broader (2)

Malate DehydrogenaseMalate dehydrogenase (decarboxylating)

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
Antisense Reduction of NADP-Malic Enzyme in Flaveria bidentis Reduces Flow of CO2 through the C4 Cycle[W][OA]
An antisense construct targeting the C4 isoform of NADP-malic enzyme (ME), the primary enzyme decarboxylating malate in bundle… 
Highly Cited
2011
Highly Cited
2011
Regulation of growth performance and lipid metabolism by dietary n-3 highly unsaturated fatty acids in juvenile grass carp, Ctenopharyngodon idellus.
Highly Cited
2007
Highly Cited
2007
Determining Actinobacillus succinogenes metabolic pathways and fluxes by NMR and GC-MS analyses of 13C-labeled metabolic product isotopomers.
Highly Cited
2007
Highly Cited
2007
The effect of NADP‐dependent malic enzyme expression and anaerobic C4 metabolism in Escherichia coli compared with other anaplerotic enzymes
Aims:  To understand the modification of C4‐metabolism under anaerobic glycolysis condition by overexpressing anaplerotic enzymes… 
2003
2003
Decrease in malate dehydrogenase activities in peripheral leucocytes of type 1 diabetic dogs.
Review
2001
Review
2001
NADP‐malic enzyme from plants: a ubiquitous enzyme involved in different metabolic pathways
Highly Cited
2000
Highly Cited
2000
Aberrant chloroplasts in transgenic rice plants expressing a high level of maize NADP-dependent malic enzyme
Abstract. NADP-dependent malic enzyme (NADP-ME) is a major decarboxylating enzyme in NADP-ME-type C4 species such as maize and… 
Highly Cited
1995
Highly Cited
1995
Primary Metabolism in Plant Defense (Regulation of a Bean Malic Enzyme Gene Promoter in Transgenic Tobacco by Developmental and Environmental Cues)
NADP-dependent malic enzyme (NADP-ME, EC 1.1.1.40) catalyzes the oxidative decarboxylation of malate to pyruvate, producing CO2… 
1983
1983
Renal malate dehydrogenase-activities during experimental and chronic human pyelonephritis (P.N.).
Highly Cited
1980
Highly Cited
1980
Electrophoretic evidence for two species of Anguilla leptocephali in the Sargasso Sea
Schmidt1,2 produced indirect evidence that in order to reproduce the European eel (Anguilla anguilla) migrates to a definite zone… 
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