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N-desisopropylpropranolol

Known as: N-deisopropylpropranolol 
National Institutes of Health

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3 relations

Narrower (1)

N-desisopropylpropranolol hydrochloride

Broader (1)

Propranolol
analogs & derivatives

Papers overview

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2005
2005
LC/MS/MS Determination of Propranolol and Its Metabolites 4-Hydroxypropranolol and N-Desisopropylpropranolol in Rat Plasma
  • H. Min
  • 2005
  • Corpus ID: 100708507
To establish an LC/MS/MS method for the determination of propranolol and its metabolites 4- hydroxypropranolol and N… 
2001
2001
Side-chain metabolism of propranolol: involvement of monoamine oxidase and aldehyde reductase in the metabolism of N-desisopropylpropranolol to propranolol glycol in rat liver.
1997
1997
beta-Adrenoreceptor antagonistic actions and mutagenicities of R(+)- and S(-)-enantiomers of N-desisopropylpropranolol and its N-acetyl conjugate.
Enantiospecific acetyl conjugation was examined in the rat liver 105000 x g supernatant (cytosol) system using racemic 1-amino-3… 
1995
1995
Determination and properties of acetyl conjugate of N-desisopropylpropranolol, AcNDP.
1-Acetamino-3-(1-naphthyloxy)-2-propanol (AcNDP) detected in human urine was formed as a metabolite of propranolol (PL) via 1… 
1992
1992
Induction of propranolol metabolism in the Hep G2 human hepatoma cell line
Abstract— Metabolism of propranolol by the human hepatoma cell line Hep G2 was studied. Although metabolism qualitatively was… 
1991
1991
In vitro cutaneous biotransformation of propranolol.
The metabolism of propranolol by human skin and by several cell preparations has been investigated in vitro. The major… 
1982
1982
An automated HPLC method for the assay of propranolol and its basic metabolites in plasma and urine.
An automated HPLC method is described for the simultaneous determination of propranolol, 4-hydroxypropranolol, and N… 
1981
1981
Chemical trapping of labile aldehyde intermediates in the metabolism of propranolol and oxprenolol.
Propranolol is N-dealkylated to N-desisopropylpropranolol (DIP) by microsomal enzymes. DIP was shown in this study to be rapidly… 
1978
1978
The contribution of propranolol metabolites to the fluorometric assay of propranolol in human plasma.
1977
1977
Studies on the contribution of active metabolites to the anticonvulsant effects of propranolol.
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