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N(2)-methylguanosine

National Institutes of Health

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7-methylguanosine

Papers overview

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2016
2016
Structural and functional analyses of the archaeal tRNA m2G/m22G10 methyltransferase aTrm11 provide mechanistic insights into site specificity of a tRNA methyltransferase that contains common RNA…
N2-methylguanosine is one of the most universal modified nucleosides required for proper function in transfer RNA (tRNA… 
2014
2014
Analysis of urinary methylated nucleosides of patients with coronary artery disease by high-performance liquid chromatography/electrospray ionization tandem mass spectrometry.
RATIONALE In recent years, methylated nucleosides have been considered to be potential biomarkers to human diseases. The early… 
2012
2012
The open reading frame TTC1157 of Thermus thermophilus HB27 encodes the methyltransferase forming N²-methylguanosine at position 6 in tRNA.
N(2)-methylguanosine (m(2)G) is found at position 6 in the acceptor stem of Thermus thermophilus tRNA(Phe). In this article, we… 
2011
2011
Formation of m2G6 in Methanocaldococcus jannaschii tRNA catalyzed by the novel methyltransferase Trm14
The modified nucleosides N2-methylguanosine and N22-dimethylguanosine in transfer RNA occur at five positions in the D and… 
2010
2010
Targeted serum metabolite profiling of nucleosides in esophageal adenocarcinoma.
Nucleosides are indicators of the whole-body turnover of transfer RNA. Based on the activity of cancer cells these molecules… 
Highly Cited
2009
Highly Cited
2009
A fast capillary electrophoresis method for separation and quantification of modified nucleosides in urinary samples.
Modified nucleosides are formed at the post-transcriptional stage by chemical modification of normal nucleosides within the… 
2008
2008
Effects of N2,N2-dimethylguanosine on RNA structure and stability: crystal structure of an RNA duplex with tandem m2 2G:A pairs.
Methylation of the exocyclic amino group of guanine is a relatively common modification in rRNA and tRNA. Single methylation (N(2… 
1974
1974
N2-guanine specific transfer RNA methyltransferase I from rat liver and leukemic rat spleen.
An enzyme was purified from rat liver and leukemic rat spleen which methylates guanosine residues in tRNA to N(2)-methylguanosine… 
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