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Mylabris

National Institutes of Health

Papers overview

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2020
2020
18-GA-Suc Modified Liposome Loading Cantharidin for Augmenting Hepatic Specificity: Preparation, Characterization, Anti-Tumor Effects and Liver-Targeting Efficiency.
2018
2018
The combination of cantharidin and antiangiogenic therapeutics presents additive antitumor effects against pancreatic cancer
Cantharidin, one of the active components of mylabris, is believed to have antitumor activity. Cantharidin selectively inhibits… 
2015
2015
Cantharidin and norcantharidin impair stemness of pancreatic cancer cells by repressing the β-catenin pathway and strengthen the cytotoxicity of gemcitabine and erlotinib.
Increasing evidence suggests that tumors are composed of a heterogeneous cell population with a small subset of cancer stem cells… 
2015
2015
Cantharidin induces DNA damage and inhibits DNA repair‐associated protein levels in NCI‐H460 human lung cancer cells
Cantharidin is one of the major compounds from mylabris and it has cytotoxic effects in many different types of human cancer… 
2015
2015
Cantharidin represses invasion of pancreatic cancer cells through accelerated degradation of MMP2 mRNA
Cantharidin is an active constituent of mylabris, a traditional Chinese medicine and is a potent and selective inhibitor of… 
2014
2014
Cantharidin induces G2/M phase arrest by inhibition of Cdc25c and Cyclin A and triggers apoptosis through reactive oxygen species and the mitochondria‑dependent pathways of A375.S2 human melanoma…
Cantharidin (CTD), a component of natural mylabris (Mylabris phalerata Pallas) was reported to have high cytotoxicity in many… 
Highly Cited
2013
Highly Cited
2013
Cantharidin and norcantharidin inhibit the ability of MCF-7 cells to adhere to platelets via protein kinase C pathway-dependent downregulation of α2 integrin
Cancer metastasis is a highly coordinated and dynamic multistep process in which cancer cells interact with a variety of host… 
2012
2012
Scutellaria baicalensis Alleviates Cantharidin-Induced Rat Hemorrhagic Cystitis through Inhibition of Cyclooxygenase-2 Overexpression
Cantharidin, an active component in mylabris, is used in traditional Chinese medicine (TCM) to treat scabies and hepatoma, but… 
Highly Cited
2006
Highly Cited
2006
Cantharidin-induced cytotoxicity and cyclooxygenase 2 expression in human bladder carcinoma cell line.
Highly Cited
2002
Highly Cited
2002
Induction of apoptosis by norcantharidin in human colorectal carcinoma cell lines: involvement of the CD95 receptor/ligand
Abstract.Purpose: Cantharidin, a natural toxin, is the active substance of mylabris and has antitumor effects in man… 
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