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Myeloid-Derived Suppressor Cells

Known as: Cell, Myeloid-Derived Suppressor, Suppressor Cells, Myeloid-Derived, Myeloid Derived Suppressor Cells 
A heterogeneous, immature population of myeloid cells that can suppress the activity of T-CELLS and NATURAL KILLER CELLS in the INNATE IMMUNE… 
National Institutes of Health

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4 relations
MicrobiologicalProcess of secretionaspects of radiation effectsphysiological aspects

Papers overview

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Highly Cited
2017
Highly Cited
2017
Entinostat Neutralizes Myeloid-Derived Suppressor Cells and Enhances the Antitumor Effect of PD-1 Inhibition in Murine Models of Lung and Renal Cell Carcinoma
Purpose: Recent advances in immunotherapy highlight the antitumor effects of immune checkpoint inhibition despite a relatively… 
Review
2013
Review
2013
Immune suppression by neutrophils and granulocytic myeloid-derived suppressor cells: similarities and differences
Neutrophils are essential effector cells in the host defense against invading pathogens. Recently, novel neutrophil functions… 
Highly Cited
2012
Highly Cited
2012
Tumor-Infiltrating Monocytic Myeloid-Derived Suppressor Cells Mediate CCR5-Dependent Recruitment of Regulatory T Cells Favoring Tumor Growth
Myeloid-derived suppressor cells (MDSCs) represent a heterogeneous population of myeloid cells in cancer patients and tumor… 
Highly Cited
2011
Highly Cited
2011
Myeloid-derived suppressor cell accumulation and function in patients with newly diagnosed glioblastoma.
To assess the accumulation of myeloid-derived suppressor cells (MDSCs) in the peripheral blood of patients with glioma and to… 
Highly Cited
2011
Highly Cited
2011
A human promyelocytic-like population is responsible for the immune suppression mediated by myeloid-derived suppressor cells.
We recently demonstrated that human BM cells can be treated in vitro with defined growth factors to induce the rapid generation… 
Highly Cited
2010
Highly Cited
2010
Characterization of Cytokine-Induced Myeloid-Derived Suppressor Cells from Normal Human Peripheral Blood Mononuclear Cells
Tumor immune tolerance can derive from the recruitment of suppressor cell populations, including myeloid-derived suppressor cells… 
Highly Cited
2010
Highly Cited
2010
Mechanism of T Cell Tolerance Induced by Myeloid-Derived Suppressor Cells
Ag-specific T cell tolerance plays a critical role in tumor escape. Recent studies implicated myeloid-derived suppressor cells… 
Highly Cited
2010
Highly Cited
2010
Bone marrow myeloid-derived suppressor cells (MDSCs) inhibit graft-versus-host disease (GVHD) via an arginase-1-dependent mechanism that is up-regulated by interleukin-13.
Myeloid-derived suppressor cells (MDSCs) are a well-defined population of cells that accumulate in the tissue of tumor-bearing… 
Highly Cited
2008
Highly Cited
2008
Reversion of immune tolerance in advanced malignancy: modulation of myeloid-derived suppressor cell development by blockade of stem-cell factor function.
Tumor growth induced a significant increase of myeloid-derived suppressor cells (MDSCs) in the tumor-bearing host. In our… 
Review
2007
Review
2007
Pathways Mediating the Expansion and Immunosuppressive Activity of Myeloid-Derived Suppressor Cells and Their Relevance to Cancer Therapy
Cancer immunotherapy has focused on inducing and expanding CTLs and improving the immune recognition of weak antigenic… 
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