Mutate

To change the genetic material of a cell. The changes (mutations) can be harmful, beneficial, or have no effect.
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
TALENs are important new tools for genome engineering. Fusions of transcription activator-like (TAL) effectors of plant… (More)
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2011
2011
Non-coding RNAs fold into precise base-pairing patterns to carry out critical roles in genetic regulation and protein synthesis… (More)
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Highly Cited
2008
Highly Cited
2008
Transposon systems are widely used for generating mutations in various model organisms. PiggyBac (PB) has recently been shown to… (More)
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Review
2001
Review
2001
Gene function in cancer can be disrupted either through genetic alterations, which directly mutate or delete genes, or epigenetic… (More)
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Highly Cited
1999
Highly Cited
1999
A fundamental goal of genetics and functional genomics is to identify and mutate every gene in model organisms such as Drosophila… (More)
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Highly Cited
1997
Highly Cited
1997
The green fluorescent protein (GFP) from the jellyfish Aequorea victoria is finding wide use as a genetic marker that can be… (More)
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Highly Cited
1995
Highly Cited
1995
NICOTINE affects many aspects of behaviour including learning and memory1,2 through its interaction with neuronal nicotinic… (More)
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Highly Cited
1991
Highly Cited
1991
A general strategy for selecting insertion mutations in mice has been devised. Constructs lacking a promoter and including a beta… (More)
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Highly Cited
1991
Highly Cited
1991
Three dominant mutations of mec-4, a gene needed for mechanosensation, cause the touch-receptor neurons of Caenorhabditis elegans… (More)
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Highly Cited
1987
Highly Cited
1987
Although vertebrate DNA is generally depleted in the dinucleotide CpG, it has recently been shown that some vertebrate genes… (More)
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