Mutagenicity Tests

Known as: Mutagen Screenings, genotoxicity testing, Mutagenicity testing 
Tests of chemical substances and physical agents for mutagenic potential. They include microbial, insect, mammalian cell, and whole animal tests.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2008
Review
2008
The comet assay is a versatile and sensitive method for measuring single- and double-strand breaks in DNA. The mechanism of… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2005
Highly Cited
2005
The performance of a battery of three of the most commonly used in vitro genotoxicity tests--Ames+mouse lymphoma assay (MLA)+in… (More)
Is this relevant?
Highly Cited
2000
Highly Cited
2000
Atthe International Workshop on Genotoxicity Test Procedures (IWGTP) held in Washington, DC, March 25-26, 1999, an expert panel… (More)
  • figure 1
  • figure 2
Is this relevant?
Review
1996
Review
1996
Chemoprevention of cancer is a means of cancer control in which the occurrence of this disease is prevented by administra tion of… (More)
  • table 1
  • table 3
Is this relevant?
Highly Cited
1996
Highly Cited
1996
BACKGROUND In addition to influences of exposure to carcinogenic compounds, the development of cancer may depend on an individual… (More)
Is this relevant?
Highly Cited
1992
Highly Cited
1992
311 chemicals were tested under code, for mutagenicity, in Salmonella typhimurium; 35 of the chemicals were tested more than once… (More)
Is this relevant?
Review
1988
Review
1988
Two alternative hypotheses are used to distinguish among the possibilities of a positive, inconclusive, or negative result in… (More)
Is this relevant?
Highly Cited
1983
Highly Cited
1983
The methods for detecting carcinogens and mutagens with the Salmonella mutagenicity test were described previously (Ames et al… (More)
  • table 2
  • table 4
  • figure 2
Is this relevant?
Highly Cited
1976
Highly Cited
1976
Escherichia coli strain WP2 and its repair-deficient derivatives are suitable strains for mutagen screening. In these strains… (More)
Is this relevant?
Highly Cited
1975
Highly Cited
1975
About 300 carcinogens and non-carcinogens of a wide variety of chemical types have been tested for mutagenicity in the simple… (More)
  • table 1
  • table 1
Is this relevant?