Skip to search formSkip to main contentSkip to account menu

Mustard Prodrug

A mustard compound that gets converted to an active mustard alkylating agent at a tumor site, causing DNA cross-linking. These compounds may be used… 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
Abstract 453: Identification of human oxidoreductases involved in the hypoxia-dependent activation of bioreductive prodrugs
Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC Hypoxia occurs in most human tumors and is… 
2006
2006
Study of SingleAdministration of Antibody-Directed Enzyme ProdrugTherapy with the Recombinant Anti ^ Carcinoembryonic Antigen Antibody-Enzyme Fusion Protein MFECP 1 and a Bis-Iodo Phenol Mustard…
Purpose: Antibody-directed enzyme prodrug therapy is a two-stage treatment whereby a tumor-targeted antibody-enzyme complex… 
2004
2004
Radiosynthesis of 4-[(2-chloroethyl)(2-[(11)C]ethyl)amino]-phenoxycarbonyl-l-glutamic acid a half mustard prodrug as a potential probe for imaging antibody- and gene-directed enzyme prodrug therapy…
2002
2002
P17. Radiolabelling of a half mustard prodrug for antibody-directed enzyme prodrug therapy
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)