Multiplex Ligation-Dependent Probe Amplification

Known as: MLPA, Multiplex Ligation Dependent Probe Amplification 
A type of high-throughput, multiplex PCR method used to determine abnormal DNA copy number changes of up to 50 genomic DNA or RNA sequences with a… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1990-2018
05010015019902018

Papers overview

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Highly Cited
2010
Highly Cited
2010
PURPOSE Metastasis from uveal melanoma occurs almost exclusively with tumors showing chromosome 3 loss. We used multiplex… (More)
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2010
2010
PURPOSE To determine intratumor genetic heterogeneity in uveal melanoma (UM) by multiplex ligation-dependent probe amplification… (More)
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2009
2009
PURPOSE To evaluate multiplex ligation-dependent probe amplification (MLPA) of uveal melanoma as a predictive tool for metastatic… (More)
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2007
2007
To estimate the contribution of single and multi-exon NF1 gene copy-number changes to the NF1 mutation spectrum, we analysed a… (More)
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2006
2006
OBJECTIVES To evaluate the efficacy of Multiplex Ligation-dependent Probe Amplification (MLPA) technique in comparison with the… (More)
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2006
2006
Spinal muscular atrophy (SMA) is an autosomal recessive disease caused by decreased levels of survival motor neuron protein (SMN… (More)
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Highly Cited
2004
Highly Cited
2004
Multiplex ligation-dependent probe amplification (MLPA) is a recently described method for detecting gross deletions or… (More)
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Highly Cited
2004
Highly Cited
2004
Genomic deletions and duplications play an important role in the etiology of human disease. Versatile tests are required to… (More)
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2004
2004
Subtelomeric rearrangements are responsible for 5% to 10% of cases of unexplained mental retardation. Despite their clinical… (More)
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Highly Cited
2002
Highly Cited
2002
We describe a new method for relative quantification of 40 different DNA sequences in an easy to perform reaction requiring only… (More)
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