Multiple Transversion Abnormalities

Known as: Multiple Transversion Mutations, Transversion Mutations 
Multiple point mutations in a DNA sequence from eukaryotic or prokaryotic organisms in which each mutation occurs by substitution of a purine base… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1972-2017
051019722017

Papers overview

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Highly Cited
2011
Highly Cited
2011
Somatic mutations of mtDNA are implicated in the aging process, but there is no universally accepted method for their accurate… (More)
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Highly Cited
2009
Highly Cited
2009
PURPOSE The impact of epidermal growth factor receptor (EGFR) and KRAS genotypes on outcomes with erlotinib or gefitinib therapy… (More)
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Highly Cited
2008
Highly Cited
2008
PURPOSE KRAS mutations are found in approximately 25% of lung adenocarcinomas in Western countries and, as a group, have been… (More)
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Highly Cited
2006
Highly Cited
2006
Analysis of LTR retrotransposon structures in five diploid angiosperm genomes uncovered very different relative levels of… (More)
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Highly Cited
2006
Highly Cited
2006
A central mystery in the function of site-specific DNA-binding proteins is the detailed mechanism for rapid location and binding… (More)
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Highly Cited
2001
Highly Cited
2001
Oxygen radicals, which can be produced through normal cellular metabolism, are thought to play an important role in mutagenesis… (More)
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Highly Cited
1999
Highly Cited
1999
DNA damage generated by oxidant byproducts of cellular metabolism has been proposed as a key factor in cancer and aging. Oxygen… (More)
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Highly Cited
1996
Highly Cited
1996
We describe a new method for random mutagenesis of DNA based on the use of a mixture of triphosphates of nucleoside analogues… (More)
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Highly Cited
1989
Highly Cited
1989
A rapid nonradioactive approach to the diagnosis of sickle cell anemia is described based on an allele-specific polymerase chain… (More)
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Highly Cited
1982
Highly Cited
1982
The pattern of point mutations is inferred from nucleotide substitutions in pseudogenes. The pattern obtained suggests that… (More)
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