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Multiple Transversion Abnormalities

Known as: Multiple Transversion Mutations, Transversion Mutations 
Multiple point mutations in a DNA sequence from eukaryotic or prokaryotic organisms in which each mutation occurs by substitution of a purine base… 
National Institutes of Health

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Transversion Mutation

Papers overview

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Review
2001
Review
2001
Mismatch repair in correction of replication errors and processing of DNA damage
The primary role of mismatch repair (MMR) is to maintain genomic stability by removing replication errors from DNA. This repair… 
Highly Cited
2001
Highly Cited
2001
Mutagenesis by O(6)-methyl-, O(6)-ethyl-, and O(6)-benzylguanine and O(4)-methylthymine in human cells: effects of O(6)-alkylguanine-DNA alkyltransferase and mismatch repair.
Double-stranded and gapped shuttle vectors were used to study mutagenesis in human cells by O(6)-methyl (m(6)G)-, O(6)-ethyl (e(6… 
Highly Cited
2000
Highly Cited
2000
Detection of a common mutation in the RSH or Smith-Lemli-Opitz syndrome by a PCR-RFLP assay: IVS8-G-->C is found in over sixty percent of US propositi.
The RSH or Smith-Lemli-Opitz syndrome (SLOS) is a relatively common autosomal recessive disorder of cholesterol biosynthesis… 
1999
1999
p53 over‐expression and p53 mutations in colon carcinomas: Relation to dietary risk factors
Epidemiological studies have suggested that dietary factors may differently affect p53‐dependent and p53‐independent pathways to… 
1998
1998
Characterization of the CBF2 Binding Site within the Epstein-Barr Virus Latency C Promoter and Its Role in Modulating EBNA2-Mediated Transactivation
ABSTRACT The Epstein-Barr virus (EBV) EBNA2 protein is a transcriptional activator that regulates viral and cellular gene… 
Highly Cited
1991
Highly Cited
1991
Activating mutations at codon 61 of the c-Ha-ras gene in thin-tissue sections of tumors induced by aristolochic acid in rats and mice.
1991
1991
Ultraviolet mutational spectrum in a shuttle vector propagated in xeroderma pigmentosum lymphoblastoid cells and fibroblasts.
Highly Cited
1989
Highly Cited
1989
Escherichia coli mutY gene encodes an adenine glycosylase active on G-A mispairs.
Mutations in the mutY gene of Escherichia coli confer hypermutability reflecting G.C to T.A transversion mutations and result in… 
1989
1989
Influence of uvrB and pKM101 on the spectrum of spontaneous, UV- and gamma-ray-induced base substitutions that revert hisG46 in Salmonella typhimurium.
Highly Cited
1988
Highly Cited
1988
Molecular analysis of mutations induced in human cells by N‐ethyl‐N‐nitrosourea
Mutational activation of cellular proto‐oncogenes is an important event in the pathogenesis of chemically induced tumors. We have… 
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