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Multifunctional Enzymes

Known as: Enzymes, Multifunctional, Multifunctional Enzymes [Chemical/Ingredient] 
Molecules that contain multiple active sites which are used to catalyze more than one enzymatic reaction. Proteins in this class generally contain… 
National Institutes of Health

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In BloodMultienzyme ComplexesProcess of secretionantagonists & inhibitors

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PrimPol protein, human

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Modular Organization of the Thermobifida fusca Exoglucanase Cel6B Impacts Cellulose Hydrolysis and Designer Cellulosome Efficiency
Cellulose deconstruction can be achieved by three distinct enzymatic paradigms: free enzymes, multifunctional enzymes, and self… 
Review
2016
Review
2016
The safety profile of vorinostat (suberoylanilide hydroxamic acid) in hematologic malignancies: A review of clinical studies.
2016
2016
The GH51 α-l-arabinofuranosidase from Paenibacillus sp. THS1 is multifunctional, hydrolyzing main-chain and side-chain glycosidic bonds in heteroxylans
BackgroundConceptually, multi-functional enzymes are attractive because in the case of complex polymer hydrolysis having two or… 
2015
2015
Comparison of 10,11‐Dehydrocurvularin Polyketide Synthases from Alternaria cinerariae and Aspergillus terreus Highlights Key Structural Motifs
Iterative type I polyketide synthases (PKSs) from fungi are multifunctional enzymes that use their active sites repeatedly in a… 
2012
2012
Protein-Protein Interactions in the β-Oxidation Part of the Phenylacetate Utilization Pathway
Background: The phenylacetate utilization pathway (paa operon) is the main pathway for degradation of aromatic compounds. Results… 
Highly Cited
2012
Highly Cited
2012
A Global Characterization and Identification of Multifunctional Enzymes
Multi-functional enzymes are enzymes that perform multiple physiological functions. Characterization and identification of multi… 
Highly Cited
2012
Highly Cited
2012
Introducing endo-xylanase activity into an exo-acting arabinofuranosidase that targets side chains
The degradation of the plant cell wall by glycoside hydrolases is central to environmentally sustainable industries. The major… 
Review
2002
Review
2002
A survey of covalent, ionic, and radical intermediates in enzyme-catalyzed reactions.
2002
2002
Structure-function studies of the mammalian peroxisomal multifunctional enzyme type 2 (MFE-2)
Mammalian peroxisomes contain two parallel multifunctional enzymes (MFE), MFE type 1 and MFE type 2 (MFE-2), which are… 
2000
2000
Metal-ion stoichiometry of the HIV-1 RT ribonuclease H domain: evidence for two mutually exclusive sites leads to new mechanistic insights on metal-mediated hydrolysis in nucleic acid biochemistry
Abstract Crystallographic studies of the Mn2+-doped RNase H domain of human immunodeficiency virus type 1 reverse transcriptase… 
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