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MtrC protein, Neisseria gonorrhoeae

Known as: multiple transferrable resistance C protein, Neisseria gonorrhoeae 
National Institutes of Health

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3 relations

Broader (3)

Bacterial ProteinsLipoproteinsMembrane Transport Proteins

Papers overview

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2015
2015
S11.2 Efflux pumps in neisseria gonorrhoeae – cause of resistance and targets for therapeutics and vaccine?
Neisseria gonorrhoeae is the cause of the sexually transmitted infection termed gonorrhoea, which afflicts over 100 million… 
Highly Cited
2014
Highly Cited
2014
Importance of Multidrug Efflux Pumps in the Antimicrobial Resistance Property of Clinical Multidrug-Resistant Isolates of Neisseria gonorrhoeae
ABSTRACT The contribution of drug efflux pumps in clinical isolates of Neisseria gonorrhoeae that express extensively drug… 
Review
2011
Review
2011
Estradiol-Treated Female Mice as Surrogate Hosts for Neisseria gonorrhoeae Genital Tract Infections
Historically, animal modeling of gonorrhea has been hampered by the exclusive adaptation of Neisseria gonorrhoeae to humans… 
Highly Cited
2011
Highly Cited
2011
A Novel Mechanism of High-Level, Broad-Spectrum Antibiotic Resistance Caused by a Single Base Pair Change in Neisseria gonorrhoeae
ABSTRACT The MtrC-MtrD-MtrE multidrug efflux pump of Neisseria gonorrhoeae confers resistance to a diverse array of antimicrobial… 
2011
2011
Evidence for the Assembly of a Bacterial Tripartite Multidrug Pump with a Stoichiometry of 3:6:3*
The multiple transferable resistance (mTR) pump from Neisseria gonorrhoeae MtrCDE multidrug pump is assembled from the inner and… 
Highly Cited
2008
Highly Cited
2008
Clinically relevant mutations that cause derepression of the Neisseria gonorrhoeae MtrC‐MtrD‐MtrE Efflux pump system confer different levels of antimicrobial resistance and in vivo fitness
The MtrC‐MtrD‐MtrE efflux pump system confers resistance to macrolide antibiotics and antimicrobial substances of the host innate… 
Highly Cited
2007
Highly Cited
2007
Regulation of the MtrC-MtrD-MtrE efflux-pump system modulates the in vivo fitness of Neisseria gonorrhoeae.
The Neisseria gonorrhoeae MtrC-MtrD-MtrE multidrug-resistance efflux pump expels macrolide antibiotics, penicillin, and… 
Highly Cited
2005
Highly Cited
2005
Characterization of the MacA-MacB efflux system in Neisseria gonorrhoeae.
OBJECTIVES A homologue of the MacA-MacB ABC transporter of Escherichia coli, which recognizes and exports macrolides, was… 
2002
2002
Inducible, but Not Constitutive, Resistance of Gonococci to Hydrophobic Agents Due to the MtrC-MtrD-MtrE Efflux Pump Requires TonB-ExbB-ExbD Proteins
ABSTRACT The MtrC-MtrD-MtrE efflux pump possessed by Neisseria gonorrhoeae is very similar to the MexA-MexB-OprM efflux pump of… 
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