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Monoclonal Antibody MGA271

Known as: MGA271 
An Fc-domain optimized, humanized monoclonal antibody directed against cancer stem cells (CSCs), with potential immunomodulating and antineoplastic… Expand
National Institutes of Health

Papers overview

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2017
2017
TPS2596Background: Enoblituzumab, is an Fc optimized humanized IgG1 monoclonal antibody that binds to B7-H3 (CD276), a member of… Expand
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2016
2016
256 Background: B7-H3 (CD276), part of the B7 superfamily, has been shown to play an immunomodulatory role, however its… Expand
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2015
2015
Interim results of an ongoing Phase I, dose escalation study of MGA271 (Fc-optimized humanized anti-B7-H3 monoclonal antibody) in… Expand
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2015
2015
Meeting abstracts MGA271 is an Fc optimized humanized IgG1 monoclonal antibody that binds to B7-H3 (CD276), a member of the B7… Expand
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Highly Cited
2012
Highly Cited
2012
Purpose: The goal of this research was to harness a monoclonal antibody (mAb) discovery platform to identify cell-surface… Expand
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2012
2012
Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL Antigens that are tumor-specific or over-expressed… Expand
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2012
2012
Purpose: The goal of this research was to harness a monoclonal antibody (mAb) discovery platform to identify cell-surface… Expand
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