Skip to search form
Skip to main content
Skip to account menu
Semantic Scholar
Semantic Scholar's Logo
Search 209,972,813 papers from all fields of science
Search
Sign In
Create Free Account
Monoclonal Antibody MGA271
Known as:
MGA271
An Fc-domain optimized, humanized monoclonal antibody directed against cancer stem cells (CSCs), with potential immunomodulating and antineoplastic…
Expand
National Institutes of Health
Create Alert
Alert
Related topics
Related topics
1 relation
antigen binding
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
A phase 1, open-label, dose escalation study of enoblituzumab (MGA271) in pediatric patients with B7-H3-expressing relapsed or refractory solid tumors.
K. Desantes
,
J. Maris
,
+8 authors
P. Sondel
2017
Corpus ID: 56756843
TPS2596Background: Enoblituzumab, is an Fc optimized humanized IgG1 monoclonal antibody that binds to B7-H3 (CD276), a member of…
Expand
2016
2016
The relationship of B7H3 expression to androgen and prostate cancer outcomes in a large natural history cohort of men undergoing prostatectomy.
A. Ross
,
B. Benzon
,
+14 authors
F. Feng
2016
Corpus ID: 79437953
256 Background: B7-H3 (CD276), part of the B7 superfamily, has been shown to play an immunomodulatory role, however its…
Expand
Highly Cited
2015
Highly Cited
2015
Interim results of an ongoing Phase I, dose escalation study of MGA271 (Fc-optimized humanized anti-B7-H3 monoclonal antibody) in patients with refractory B7-H3-expressing neoplasms or neoplasms…
J. Powderly
,
G. Cote
,
+13 authors
B. Chmielowski
Journal of Immunotherapy for Cancer
2015
Corpus ID: 74582457
Meeting abstracts MGA271 is a humanized IgG1 monoclonal antibody-targeting B7-H3 (CD276), a member of the B7 family. MGA271 has…
Expand
2015
2015
A Phase I, open-label, dose escalation study of MGA271 in combination with ipilimumab in patients with B7-H3-expressing melanoma, squamous cell cancer of the head and neck or non-small cell lung…
W. Urba
,
B. Chmielowski
,
+7 authors
N. Rizvi
Journal of Immunotherapy for Cancer
2015
Corpus ID: 33160669
Meeting abstracts MGA271 is an Fc optimized humanized IgG1 monoclonal antibody that binds to B7-H3 (CD276), a member of the B7…
Expand
Highly Cited
2012
Highly Cited
2012
Development of an Fc-Enhanced Anti–B7-H3 Monoclonal Antibody with Potent Antitumor Activity
D. Loo
,
R. Alderson
,
+21 authors
P. Moore
Clinical Cancer Research
2012
Corpus ID: 23415250
Purpose: The goal of this research was to harness a monoclonal antibody (mAb) discovery platform to identify cell-surface…
Expand
2012
2012
Abstract 2725: Preclinical development of an Fc-enhanced anti-B7-H3 monoclonal antibody with potent anti-tumor activity
D. Loo
,
R. Alderson
,
+19 authors
P. Moore
2012
Corpus ID: 70433635
Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL Antigens that are tumor-specific or over-expressed…
Expand
2012
2012
Cancer Therapy : Preclinical Development of an Fc-Enhanced Anti – B 7-H 3 Monoclonal Antibody with Potent Antitumor Activity
D. Loo
,
R. Alderson
,
+21 authors
P. Moore
2012
Corpus ID: 46374812
Purpose: The goal of this research was to harness a monoclonal antibody (mAb) discovery platform to identify cell-surface…
Expand
By clicking accept or continuing to use the site, you agree to the terms outlined in our
Privacy Policy
(opens in a new tab)
,
Terms of Service
(opens in a new tab)
, and
Dataset License
(opens in a new tab)
ACCEPT & CONTINUE