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Molecular Target
Every point of difference between premalignant or malignant cells and their normal counterparts is a potential target of opportunity for drug…
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National Institutes of Health
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Effect of Pro-Inflammatory Cytokine IL-1β, on Urotensin II Gene Expression in Human Lung Cancer Cells
H. Okuyan
,
M. Terzi
,
Cansu Önlen Güneri
,
Meral Urhan Küçük
Konuralp Tip Dergisi
2018
Corpus ID: 56021053
Amac: Akciger kanseri dunya capinda en olumcul kanser turudur. Akciger kanseri hastalarinin kotu prognozu ve etkili tedavinin…
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2018
2018
LncRNA GHET 1 predicts a poor prognosis of the patients with non-small cell lung cancer
Qi-Ming Shen
,
H.-Y. Wang
,
S. Xu
2018
Corpus ID: 145034099
Abstract. – OBJECTIVE: Long non-coding RNAs (LcRNAs) is related to lung cancer progression. This study aimed at exploring lncRNA…
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2017
2017
Instructions for use Title Clusterin is a potential molecular predictor for ovarian cancer patient ' s survival : targeting Clusterinimproves response to paclitaxel
M. Hassan
,
H. Watari
,
+5 authors
N. Sakuragi
2017
Corpus ID: 21790233
Background: Clusterin is a cytoprotective chaperone protein involved in numerous physiological processes, carcinogenesis, tumor…
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2016
2016
YM 155 down-regulates survivin and induces PUMA-dependent apoptosis in oral squamous cell carcinoma cells
Xing-Hua Yang
,
Lin-Hui Peng
,
Yan-Li Shi
2016
Corpus ID: 39351166
Objective: YM155, which inhibits the anti-apoptotic protein survivin, is known to exert anti-tumor effects in various cancers…
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2015
2015
TRAF 4 promotes the growth and invasion of colon cancer through the Wnt / β-catenin pathway
Ke Yang
,
Feng Wang
,
Jianjun Han
2015
Corpus ID: 38457190
The tumor necrosis factor receptor-associated factor 4 (TRAF4) has been linked to carcinogenesis. However, the role of TRAF4 in…
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2014
2014
The BRCA 2 gene is a potential molecular target during 5-fluorouracil therapy in human oral cancer cells
Y. Nakagawa
,
A. Kajihara
,
+4 authors
T. Ohnishi
2014
Corpus ID: 47618719
5-Fluorouracil (5-FU) is widely used in clinical cancer therapy. It is commonly used either alone or in combination with other…
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2012
2012
New Leads for Personalized Medicine in Pediatrics: Targeting Syk for Treatment of Serious Pediatric Illnesses
F. Uçkun
2012
Corpus ID: 72483979
Copyright: © 2012 Uckun FM. This is an open-access article distributed under the terms of the Creative Commons Attribution…
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Review
2011
Review
2011
A Review on Local Chemotherapy for Treatment of Retinoblastoma
Fariba Ghassemi
,
M. Abdehag
,
Ramak Roohipoor
,
R. Karkhaneh
,
M. Ahmadabadi
2011
Corpus ID: 74259011
Retinoblastoma is the most common primary intraocular malignancy of childhood. Current treatments for retinoblastoma have led to…
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2010
2010
Prostate cancer: gene fusions
Nick Groves-Kirkby
Nature reviews. Urology
2010
Corpus ID: 5901458
volume 7 | sePtemBer 2010 | 473 research highlights two studies, published in Nature Genetics and Nature Medicine, have shed…
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1999
1999
Advances in Brief Gene Therapy with Dominant-negative Stat 3 Suppresses Growth of the Murine Melanoma B 16 Tumor in Vivo 1
G. Niu
,
R. Heller
,
+5 authors
Hua Yu
1999
Corpus ID: 7662793
Whereas signal transducers and activators of transcription were originally discovered as mediators of normal cytokine signaling…
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