Modified Release Dosage Form

Known as: Modified Release, Modified Release Dose Form 
A solid, semi-solid, solution or suspension exhibiting an altered inherent rate of release of active and/or inert ingredient(s).
National Institutes of Health

Papers overview

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2014
2014
First Multicenter Study of Modified Release Phosphatidylcholine “LT-02” in Ulcerative Colitis: A Randomized, Placebo-Controlled Trial in Mesalazine-Refractory Courses
OBJECTIVES:Phosphatidylcholine is a key component of the mucosal barrier. Treatment with modified release phosphatidylcholine… (More)
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2010
2010
Efficacy, tolerability and pharmacokinetics of a modified release formulation of ADX10059, a negative allosteric modulator of metabotropic glutamate receptor 5: an esophageal pH-impedance study in…
BACKGROUND Animal studies show metabotropic glutamate receptor 5 inhibition reduces transient lower esophageal sphincter… (More)
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2008
2008
The efficacy of self-monitoring of blood glucose in the management of patients with type 2 diabetes treated with a gliclazide modified release-based regimen. A multicentre, randomized, parallel-group…
AIM To determine if therapeutic management programmes for type 2 diabetes that include self-monitoring of blood glucose (SMBG… (More)
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2008
2008
Fabrication of Modified Release Tablet Formulation of Metoprolol Succinate using Hydroxypropyl Methylcellulose and Xanthan Gum
The present investigation was undertaken to fabricate modified release tablet of metoprolol succinate using hydroxypropyl… (More)
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2006
2006
Preparation and characterization of eudragit retard nanosuspensions for the ocular delivery of cloricromene.
The purpose of this study was to improve the stability of cloricromene (AD6) in ophthalmic formulations and its drug availability… (More)
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Highly Cited
2005
Highly Cited
2005
Conversion of stable kidney transplant recipients from a twice daily Prograf-based regimen to a once daily modified release tacrolimus-based regimen.
UNLABELLED Modified release (MR) tacrolimus is an extended release formulation administered once daily (qD). The purpose of this… (More)
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Highly Cited
2004
Highly Cited
2004
GUIDE study: double-blind comparison of once-daily gliclazide MR and glimepiride in type 2 diabetic patients.
BACKGROUND Progressive beta-cell failure is a characteristic feature of type 2 diabetes; consequently, beta-cell secretagogues… (More)
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2004
2004
Conversion of stable liver transplant recipients from a twice-daily Prograf-based regimen to a once-daily modified release tacrolimus-based regimen.
INTRODUCTION Modified release (MR) tacrolimus is an extended release formulation administered once daily. The purpose of this… (More)
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2003
2003
Preparation and in vitro evaluation of modified release ketoprofen microsponges.
Microsponges containing ketoprofen and Eudragit RS 100 were prepared by quasi-emulsion solvent diffusion method. The effects of… (More)
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Highly Cited
1998
Highly Cited
1998
Evaluation and comparison of dissolution data derived from different modified release dosage forms: an alternative method.
Dissolution testing is an essential requirement for the development, establishment of in vitro dissolution and in vivo… (More)
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