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Modified Release Dosage Form

Known as: Modified Release, Modified Release Dose Form 
A solid, semi-solid, solution or suspension exhibiting an altered inherent rate of release of active and/or inert ingredient(s).
National Institutes of Health

Papers overview

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Highly Cited
2017
Highly Cited
2017
Development of modified release 3D printed tablets (printlets) with pharmaceutical excipients using additive manufacturing.
The aim of this study was to manufacture 3D printed tablets (printlets) from enteric polymers by single filament fused deposition… Expand
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Highly Cited
2008
Highly Cited
2008
An in vivo comparison of intestinal pH and bacteria as physiological trigger mechanisms for colonic targeting in man.
Targeting the colon for site-specific oral delivery can exploit one of two main physiological triggers; the intestinal pH changes… Expand
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Highly Cited
2005
Highly Cited
2005
CONVERSION OF STABLE KIDNEY TRANSPLANT RECIPIENTS FROM A TWICE DAILY PROGRAF BASED REGIMEN TO A ONCE DAILY MODIFIED RELEASE TACROLIMUS BASED REGIMEN
  • R. Alloway
  • Transplantation proceedings
  • 2005
    • Corpus ID: 25500194
UNLABELLED Modified release (MR) tacrolimus is an extended release formulation administered once daily (qD). The purpose of this… Expand
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Highly Cited
2004
Highly Cited
2004
Development of a controlled release formulation based on SLN and NLC for topical clotrimazole delivery.
Solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) are colloidal carrier systems providing controlled… Expand
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Highly Cited
2004
Highly Cited
2004
GUIDE study: double‐blind comparison of once‐daily gliclazide MR and glimepiride in type 2 diabetic patients
Background  Progressive β‐cell failure is a characteristic feature of type 2 diabetes; consequently, β‐cell secretagogues are… Expand
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Highly Cited
2004
Highly Cited
2004
Development of a controlled release formulation based on SLN and NLC for topical clotrimazole delivery
  • E. B. Soutoa, S. A. Wissinga, C. M. Barbosab, R. Müllera
  • 2004
    • Corpus ID: 4635524
Solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) are colloidal carrier systems providing controlled… Expand
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Highly Cited
2003
Highly Cited
2003
Preparation and in vitro evaluation of modified release ketoprofen microsponges.
Microsponges containing ketoprofen and Eudragit RS 100 were prepared by quasi-emulsion solvent diffusion method. The effects of… Expand
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Highly Cited
2001
Highly Cited
2001
Intercalation compounds of hydrotalcite-like anionic clays with antiinflammatory agents--I. Intercalation and in vitro release of ibuprofen.
Hydrotalcite-like compounds are layered solids having positively charged layers and interlayer charge-compensating anions. The… Expand
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Highly Cited
1998
Highly Cited
1998
Evaluation and comparison of dissolution data derived from different modified release dosage forms: an alternative method.
  • V. Pillay, R. Fassihi
  • Journal of controlled release : official journal…
  • 1998
    • Corpus ID: 28595735
Dissolution testing is an essential requirement for the development, establishment of in vitro dissolution and in vivo… Expand
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Highly Cited
1998
Highly Cited
1998
Gamma irradiation effects on poly(DL-lactictide-co-glycolide) microspheres.
Gamma radiation treatment plays an increasingly important role in the sterilization/sanitization of pharmaceutical products… Expand
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