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Mimosine

Known as: Leucaenol, L-Mimosine, Leucenol 
3-Hydroxy-4-oxo-1(4H)-pyridinealanine. An antineoplastic alanine-substituted pyridine derivative isolated from Leucena glauca.
National Institutes of Health

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In Bloodagonistsanalogs & derivativesantagonists & inhibitors

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mimosinamine

Papers overview

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2003
2003
The mid genes of Rhizobium sp strain TAL1145 are required for degradation of mimosine into 3-hydroxy-4-pyridone and are inducible by mimosine.
Mimosine is a toxin present in the tree-legume leucaena (Leucaena leucocephala), including its root nodules and the root exudates… 
2001
2001
Reproductive performance of South African indigenous goats inoculated with DHP-degrading rumen bacteria and maintained on Leucaena leucocephala/grass mixture and natural pasture.
Highly Cited
1998
Highly Cited
1998
Antiretroviral effects of deoxyhypusyl hydroxylase inhibitors: a hypusine-dependent host cell mechanism for replication of human immunodeficiency virus type 1 (HIV-1).
Highly Cited
1996
Highly Cited
1996
Mimosine arrests the cell cycle after cells enter S-phase.
L-Mimosine (beta-N-[3-hydroxy-4-pyridone]-alpha-aminopropionic acid)--a rare amino acid derived from Mimosa and Leucaena plants… 
Highly Cited
1996
Highly Cited
1996
Mimosine Targets Serine Hydroxymethyltransferase (*)
The plant amino acid, mimosine, is an extremely effective inhibitor of DNA replication in mammalian cells (Mosca, P. J., Dijkwel… 
Highly Cited
1996
Highly Cited
1996
Mimosine blocks cell cycle progression by chelating iron in asynchronous human breast cancer cells.
Mimosine is a toxic nonprotein amino acid that is a major constituent of the tropical legumes Leucaena and Mimosa. Mimosine has… 
Highly Cited
1995
Highly Cited
1995
Detection of a sub‐set of polysomal mRNAs associated with modulation of hypusine formation at the G1‐S boundary Proposal of a role for eIF‐5A in onset of DNA replication
1994
1994
Negative regulation of histone H1 kinase expression by mimosine, a plant amino acid.
The plant amino acid mimosine has been shown to reversibly arrest mammalian cells in late G1 phase of the cell cycle. However… 
1994
1994
The role of cell cycle redistribution in radiosensitization: implications regarding the mechanism of fluorodeoxyuridine radiosensitization.
1993
1993
Cell cycle phase‐dependent effect of retinoic acid on the induction of granulocytic differentiation in HL‐60 promyelocytic leukemia cells
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