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Micellar Paclitaxel

A systemic administered polymeric micelle containing paclitaxel that may be used for chronic inflammatory diseases, such as rheumatoid arthritis and… 
National Institutes of Health

Related topics

Related topics

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Microtubule Process

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
The solubility-permeability interplay: mechanistic modeling and predictive application of the impact of micellar solubilization on intestinal permeation.
Surfactants are routinely employed to increase the apparent aqueous solubility of poorly soluble drugs. Yet the impact of… 
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Review
2010
Review
2010
Nanomicellar formulations for sustained drug delivery: strategies and underlying principles.
Micellar delivery systems smaller than 100 nm can be readily prepared. While micelles allow a great depth of tissue penetration… 
Highly Cited
2008
Highly Cited
2008
Determination of paracetamol and its main impurity 4-aminophenol in analgesic preparations by micellar electrokinetic chromatography.
A micellar electrokinetic chromatographic (MEKC) method was developed for the quality control of paracetamol containing… 
2007
2007
Evaluation of the effect of SMA–pirarubicin micelles on colorectal cancer liver metastases and of hyperbaric oxygen in CBA mice
Tetrahydropyranyladriamycin (THP or pirarubicin) destroys tumors via several mechanisms; one of which involves the production of… 
Review
2005
Review
2005
Micellar solubilization of drugs.
PURPOSE Micellar solubilization is a powerful alternative for dissolving hydrophobic drugs in aqueous environments. In this work… 
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Highly Cited
2005
Highly Cited
2005
Separation and determination of lignans from seeds of Schisandra species by micellar electrokinetic capillary chromatography using ionic liquid as modifier.
In this paper, a micellar electrokinetic chromatographic (MEKC) method using ionic liquid as modifier for the quantification of… 
Highly Cited
2004
Highly Cited
2004
Assessment of the effects of sodium dodecyl sulfate on the buccal permeability of caffeine and estradiol.
The concentration-dependent effects of sodium dodecyl sulfate (SDS) on the in vitro permeability of the buccal mucosa were… 
2003
2003
Intestinal absorption of mixed micellar phylloquinone (vitamin K1) is unreliable in infants with conjugated hyperbilirubinaemia: implications for oral prophylaxis of vitamin K deficiency bleeding
Objective: To compare the pharmacokinetics and efficacy of oral versus intravenous mixed micellar vitamin K prophylaxis in… 
Highly Cited
2001
Highly Cited
2001
Determination of bioactive diterpenoids from Andrographis paniculata by micellar electrokinetic chromatography.
The present paper describes the development of a micellar electrokinetic chromatographic (MEKC) method for simultaneous… 
Highly Cited
1982
Highly Cited
1982
The role of surfactants in the release of very slightly soluble drugs from tablets.
The ability of surfactants to accelerate the in vitro dissolution of very slightly soluble drugs has been ascribed to wetting and… 
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