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Micellar Paclitaxel

A systemic administered polymeric micelle containing paclitaxel that may be used for chronic inflammatory diseases, such as rheumatoid arthritis and… Expand
National Institutes of Health

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Related topics

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Microtubule Process

Papers overview

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Highly Cited
2011
Highly Cited
2011
The solubility-permeability interplay: mechanistic modeling and predictive application of the impact of micellar solubilization on intestinal permeation.
Surfactants are routinely employed to increase the apparent aqueous solubility of poorly soluble drugs. Yet the impact of… Expand
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Review
2010
Review
2010
Nanomicellar formulations for sustained drug delivery: strategies and underlying principles.
Micellar delivery systems smaller than 100 nm can be readily prepared. While micelles allow a great depth of tissue penetration… Expand
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Highly Cited
2008
Highly Cited
2008
Determination of paracetamol and its main impurity 4-aminophenol in analgesic preparations by micellar electrokinetic chromatography.
A micellar electrokinetic chromatographic (MEKC) method was developed for the quality control of paracetamol containing… Expand
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2007
2007
Evaluation of the effect of SMA–pirarubicin micelles on colorectal cancer liver metastases and of hyperbaric oxygen in CBA mice
Tetrahydropyranyladriamycin (THP or pirarubicin) destroys tumors via several mechanisms; one of which involves the production of… Expand
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Highly Cited
2005
Highly Cited
2005
Separation and determination of lignans from seeds of Schisandra species by micellar electrokinetic capillary chromatography using ionic liquid as modifier.
In this paper, a micellar electrokinetic chromatographic (MEKC) method using ionic liquid as modifier for the quantification of… Expand
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2004
2004
Assessment of the effects of sodium dodecyl sulfate on the buccal permeability of caffeine and estradiol.
The concentration-dependent effects of sodium dodecyl sulfate (SDS) on the in vitro permeability of the buccal mucosa were… Expand
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2003
2003
Influence of micelle solubilization by tocopheryl polyethylene glycol succinate (TPGS) on solubility enhancement and percutaneous penetration of estradiol.
The effect of micellar solubilization on the enhancement of the solubility and percutaneous penetration of estradiol by the… Expand
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2003
2003
Intestinal absorption of mixed micellar phylloquinone (vitamin K1) is unreliable in infants with conjugated hyperbilirubinaemia: implications for oral prophylaxis of vitamin K deficiency bleeding
Objective: To compare the pharmacokinetics and efficacy of oral versus intravenous mixed micellar vitamin K prophylaxis in… Expand
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Highly Cited
2002
Highly Cited
2002
Determination of pioglitazone hydrochloride in bulk and pharmaceutical formulations by HPLC and MEKC methods.
High Performance Liquid Chromatographic (HPLC) and Micellar Electrokinetic Chromatographic (MEKC) methods have been developed for… Expand
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1982
1982
The role of surfactants in the release of very slightly soluble drugs from tablets.
The ability of surfactants to accelerate the in vitro dissolution of very slightly soluble drugs has been ascribed to wetting and… Expand
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