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Micellar Paclitaxel

A systemic administered polymeric micelle containing paclitaxel that may be used for chronic inflammatory diseases, such as rheumatoid arthritis and… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1995-2016
012319952016

Related topics

Related topics

1 relation
Microtubule Process

Related mentions per year

Related mentions per year

1995-2017
1990200020102020
Micellar Paclitaxel
Microtubule Process

Papers overview

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2013
2013
Clinical efficacy and safety of a water-soluble micellar paclitaxel (Paccal Vet) in canine mastocytomas.
OBJECTIVE To determine the clinical efficacy and safety of a cremophor-free formulation of paclitaxel (Paccal Vet, Oasmia… (More)
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2011
2011
Paclitaxel loaded PEG(5000)-DSPE micelles as pulmonary delivery platform: formulation characterization, tissue distribution, plasma pharmacokinetics, and toxicological evaluation.
The objective of the present study was to evaluate the potential of paclitaxel loaded micelles fabricated from PEG(5000)-DSPE as… (More)
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2008
2008
Paclitaxel and cisplatin as intravesical agents against non-muscle-invasive bladder cancer.
OBJECTIVES To investigate the effects of cisplatin and paclitaxel against human bladder cancer cells in vitro, and to obtain both… (More)
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2003
2003
Influence of micelle solubilization by tocopheryl polyethylene glycol succinate (TPGS) on solubility enhancement and percutaneous penetration of estradiol.
The effect of micellar solubilization on the enhancement of the solubility and percutaneous penetration of estradiol by the… (More)
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2000
2000
Polymeric micellar paclitaxel phosphorylates Bcl-2 and induces apoptotic regression of androgen-independent LNCaP prostate tumors.
BACKGROUND Paclitaxel has been difficult to evaluate in preclinical tumor model systems because its poor solubility requires a… (More)
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Highly Cited
2000
Highly Cited
2000
Acquisition of chemoresistant phenotype by overexpression of the antiapoptotic gene testosterone-repressed prostate message-2 in prostate cancer xenograft models.
Testosterone-repressed prostate message-2 (TRPM-2) expression is highly up-regulated in normal and malignant prostate cells after… (More)
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Highly Cited
2000
Highly Cited
2000
Chemosensitization and delayed androgen-independent recurrence of prostate cancer with the use of antisense Bcl-2 oligodeoxynucleotides.
BACKGROUND Increased expression of the bcl-2 gene has been observed in prostate cancer cells after androgen withdrawal and has… (More)
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1999
1999
Targeting bcl-2 gene to delay androgen-independent progression and enhance chemosensitivity in prostate cancer using antisense bcl-2 oligodeoxynucleotides.
Bcl-2 expression is upregulated in prostate cancer cells after androgen withdrawal and is associated with the development of… (More)
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1997
1997
Anti-tumor efficacy and biodistribution of intravenous polymeric micellar paclitaxel.
The purpose of this study was to evaluate the diblock copolymer poly(DL-lactide)-block-methoxy polyethylene glycol as an i.v… (More)
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1997
1997
An investigation of the antitumour activity and biodistribution of polymeric micellar paclitaxel
 Purpose: To evaluate in vitro cytotoxicity, in vivo antitumour activity and biodistribution of a novel polymeric (poly(DL… (More)
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