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Metipranolol

Known as: (+-)-Metipranolol, Phenol, 4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)-2,3,6-trimethyl-, 1-acetate, Metipranolol [Chemical/Ingredient] 
A beta-adrenergic antagonist effective for both beta-1 and beta-2 receptors. It is used as an antiarrhythmic, antihypertensive, and antiglaucoma… 
National Institutes of Health

Related topics

Related topics

19 relations

Broader (4)

Adrenergic beta-AntagonistsAnti-Arrhythmia AgentsAntihypertensive AgentsSympatholytics

Narrower (5)

DisoratOptiPranololTorratVUFB 8227
Drug AllergyGlaucoma, Open-AngleIn BloodMetipranolol hydrochloride

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2008
2008
[Pharmacokinetics of the beta-receptor blocker metipranolol in patients with liver cirrhosis (author's transl)].
The pharmacokinetics after oral administration of the beta-blocker metipranolol (Disorat) were investigated in 20 patients with… 
1986
1986
Intracellular Calcium in Hypertension: Effect of Treatment with β‐Adrenoreceptor Blockers
Summary: The effects of perinephritis hypertension on lymphocyte and cardiac β-adrenoceptors in the rabbit were examined… 
1985
1985
Double-Blind, Randomized Crossover Study on the Coronary Therapeutic Efficacy and Tolerance of IS-5-MN (ISMO 20) in Comparison with IS-5-MN + Metipranolol (ISMO-DISORAT 20/5) and Placebo
Organic nitrates and β-blockers are effective drugs for the therapy of CHD. The two drugs have synergistic anti-ischemic effects. 
1982
1982
[Effect of selective and non-selective adrenoceptor blockade during physical work on energy metabolism and sympatho-adrenergic system (author's transl)].
The influence of an acute beta-adrenoceptor blockade on work capacity, oxygen intake, plasma catecholamines, and on energy… 
Review
1981
Review
1981
Changes of the right and left ventricles in rats exposed to intermittent high altitude hypoxia.
Significant structural, functional and metabolic differences between the right and left ventricles are present already in control… 
1980
1980
Quantitative evaluation of the development of isoprenaline-induced heart lesions.
The development of heart lesions induced by isoprenaline (ISO) was quantitatively evaluated by 203Hg-Mercurascan (MSC) which was… 
1978
1978
Effect of diuretic, beta-adrenoceptor blocking agent and their combination on elevated blood pressure and serum potassium: a cross-over study.
1. The antihypertensive effect of a new beta-adrenoceptor blocking agent, trimepranol (10--14 mg/twice daily), chlorthalidone (50… 
1978
1978
Assessment of beta-blocking activity of trimepranol in man.
The beta-blocking potency and the duration of action of trimepranol were measured in healthy volunteers using isoprenaline… 
1977
1977
Experiments in animals on the pharmacological effects of metipranolol in comparison with propranolol and pindolol.
The beta-blocking agent 1-(4-acetoxy-2,3,5-trimethylphenyloxy)-3-isopropylamino-propan-2-ol (metipranolol) was compared with… 
1975
1975
Adrenergic binding sites and enzyme activities in the heart of hyperthyroid rats.
In present study interactions of some adrenergic drugs with the binding of 3H-norepinephrine (NE) and response of some enzymatic…