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Methoxamine

Known as: Pseudomethoxamine, Methoxamin, Methoxamine [Chemical/Ingredient] 
An alpha-1 adrenergic agonist that causes prolonged peripheral VASOCONSTRICTION.
National Institutes of Health

Related topics

Related topics

22 relations

Broader (9)

Adrenergic AgentsAdrenergic alpha-1 Receptor AgonistsAlcoholsAmines, Sympathomimetic
In BloodLocal Anestheticsagonistsanalogs & derivatives

Narrower (5)

Methoxamine HydrochlorideMetoxamine WellcomeVasoxineVasoxyl

Papers overview

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Highly Cited
1986
Highly Cited
1986
Absence of Functioning α‐Adrenergic Receptors in Mature Canine Coronary Collaterals
To determine if mature coronary collateral vascular smooth muscle contains functioning α-adrenergic receptors, we studied 13 dogs… 
1984
1984
The action of prazosin and propylene glycol on methoxamine-induced bronchoconstriction in asthmatic subjects.
The effect of 1 mg inhaled prazosin on bronchoconstriction induced by methoxamine was investigated in seven asthmatic subjects… 
1978
1978
Methoxamine-induced increase in afterload. Effect on left ventricular performance in chronic obstructive pulmonary disease.
With a radionuclide technique, left ventricular ejection fraction and stroke volume index were measured in the basal state and… 
1977
1977
"Reverse Coronary Steal" Induced by Coronary Vasoconstriction Following Coronary Artery Occlusion in Dogs
The phenomenon of "coronary steal," i.e., the shunting of blood from ischemic to normally perfused areas of myocardium, has been… 
1975
1975
A difference in sensitivity to alpha-adrenergic agonists exhibited by detrusor and bladder neck of rabbit.
In cumulative dose-response studies, strips from bladder neck of rabbit were significantly more sensitive to stimulation with… 
1973
1973
Stimulant action of methoxamine in the isolated atria of normal and 6-propyl-2-thiouracil-fed rats.
Methoxamine showed positive inotropic and chronotropic actions in the rat atria. These actions were blocked by phentolamine, but… 
1967
1967
Acute Hemodynamic Effects of Methoxamine in Man
The circulatory effects of single intravenous injections of 0.065 mg./kg methoxamine were investigated in 5 healthy volunteer… 
1967
1967
Steric aspects of adrenergic drugs. V. Beta adrenergic blocking effects of optical isomers of methoxamine and isopropylmethoxamine.
Beta adrenergic receptor blocking actions of (-) and (+) isomers of methoxamine and related compounds were investigated in… 
1965
1965
Methoxamine and Cardiac Output in Nonanesthetized Man and During Spinal Anesthesia
Methoxamine (approximately 0.2 mg./kg. body weight; range of total dose, 4 to 30 mg.) was given by intravenous infusion to two… 
Highly Cited
1960
Highly Cited
1960
Oxygen consumption and coronary vascular tone in the isolated fibrillating dog heart.
An improved method of determining the coronary flow and myocardial oxygen consumption of the Langendorf dog heart preparation…