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Metathesaurus Source Terminology Names

Known as: SRC, Source Terminology Names (UMLS) 
National Institutes of Health

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UMLS Metathesaurus

Papers overview

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2018
2018
Association of Dasatinib With Progression-Free Survival Among Patients With Advanced Gastrointestinal Stromal Tumors Resistant to Imatinib
Importance Gastrointestinal stromal tumors (GISTs) are life-threatening when metastatic or not amenable to surgical removal. In a… 
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Review
2015
Review
2015
SAM68: Signal Transduction and RNA Metabolism in Human Cancer
Alterations in expression and/or activity of splicing factors as well as mutations in cis-acting splicing regulatory sequences… 
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2011
2011
Bivalent inhibitors of the tyrosine kinases ABL and SRC: determinants of potency and selectivity.
We recently reported a chemical genetic method for generating bivalent inhibitors of protein kinases. This method relies on the… 
Highly Cited
2008
Highly Cited
2008
Increased Activity of the Human Sperm Tyrosine Kinase SRC by the cAMP-Dependent Pathway in the Presence of Calcium1
Abstract SRC-related tyrosine kinases are suggested to play a role in the increase of sperm protein phosphotyrosine content that… 
Highly Cited
2006
Highly Cited
2006
Arrestin Serves as a Molecular Switch, Linking Endogenous α2-Adrenergic Receptor to SRC-dependent, but Not SRC-independent, ERK Activation*
Our previous studies have demonstrated that neither receptor endocytosis nor arrestin is required for ERK activation by the α2… 
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2005
2005
Iterative microarray and RNA interference-based interrogation of the SRC-induced invasive phenotype.
Src kinase has long been recognized as a factor in the progression of colorectal cancer and seems to play a specific role in the… 
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1998
1998
Formation of a stable src–AFAP‐110 complex through either an amino‐terminal or a carboxy‐terminal SH2‐binding motif
The actin‐filament–associated protein (AFAP‐110) forms a stable complex with activated variants of the Pp60c‐src (Src) non… 
Highly Cited
1993
Highly Cited
1993
Osteopetrosis in Src-deficient mice is due to an autonomous defect of osteoclasts.
Osteopetrosis is a bone modeling disorder resulting in excessive accumulation of bone matrix due to defective function of… 
Highly Cited
1992
Highly Cited
1992
Association of Fyn with the activated platelet-derived growth factor receptor: requirements for binding and phosphorylation.
Three members of the Src family of tyrosine kinases [pp60c-src (Src), p59fyn (Fyn) and pp62c-yes (Yes)] are ubiquitously… 
1990
1990
Characterization of avian retroviruses carrying activated transforming human c-src genes and of steps involved in expression of activated src-PKases in vitro.
We have isolated four activated transforming human c-src mutants derived spontaneously from viruses carrying the normal human c… 
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