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Metastatic Renal Cell Cancer

Known as: kidney cancer, metastatic, renal cell carcinoma, metastatic, Metastatic Renal Cell Carcinoma 
A renal cell cancer that has invaded the renal capsule and has spread to lymph nodes and other anatomic sites. Metastatic renal cell cancer is stage… 
National Institutes of Health

Related topics

Related topics

16 relations
Epithelial CellsEpitheliumFlank PainHematuria

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2014
Highly Cited
2014
Immunomodulatory activity of nivolumab in previously treated and untreated metastatic renal cell carcinoma (mRCC): Biomarker-based results from a randomized clinical trial.
5012 Background: Nivolumab, a fully human IgG4 programmed death-1 (PD-1) inhibitor antibody, has shown encouraging activity in… 
Review
2012
Review
2012
Sequential therapy with targeted agents in patients with advanced renal cell carcinoma: optimizing patient benefit.
Highly Cited
2007
Highly Cited
2007
Exposure-response of sunitinib in metastatic renal cell carcinoma (mRCC): A population pharmacokinetic/pharmacodynamic (PKPD) approach
5027 Background: Sunitinib malate (SU) is an oral, multitargeted tyrosine kinase inhibitor of VEGFRs and PDGFRs, and has shown… 
Review
2006
Review
2006
Phase III randomized trial of sunitinib malate (SU11248) versus interferon-alfa (IFN-α) as first-line systemic therapy for patients with metastatic renal cell carcinoma (mRCC).
LBA3 Background: Two multicenter phase II trials of 2nd line monotherapy with sunitinib (SU11248) in patients (pts) with mRCC… 
Highly Cited
2004
Highly Cited
2004
SU011248, a novel tyrosine kinase inhibitor, shows antitumor activity in second-line therapy for patients with metastatic renal cell carcinoma: Results of a phase 2 trial.
4500 Background: SU011248 is an oral multi-targeted tyrosine kinase inhibitor with anti-tumor and anti-angiogenic activity… 
Highly Cited
2002
Highly Cited
2002
A pilot study of thalidomide in patients with progressive metastatic renal cell carcinoma
The highly vascular nature of renal cell carcinoma (RCC) suggests that angiogenesis inhibition may be therapeutic for patients… 
Highly Cited
2001
Highly Cited
2001
Radio frequency ablation of lung metastases from renal cell carcinoma.
Review
1997
Review
1997
Interleukin-2-based therapy for metastatic renal cell cancer: the Cytokine Working Group experience, 1989-1997.
PURPOSE This article reviews long-term follow-up data from three phase II studies conducted by the Cytokine Working Group from… 
Highly Cited
1995
Highly Cited
1995
NG-methyl-L-arginine, an inhibitor of nitric oxide synthase, reverses interleukin-2-induced hypotension.
OBJECTIVE To evaluate the role of NG-methyl-L-arginine as a modulator of the hyperdynamic shock induced by the administration of… 
Review
1986
Review
1986
Regression of metastatic renal cell carcinoma: a case report and literature review.
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