Metastatic Malignant Neoplasm to the Leptomeninges

Known as: cancer, metastatic to leptomeninges, leptomeningeal carcinoma, leptomeningitis, carcinomatous 
A serious problem that may occur in cancer in which cancer cells spread from the original (primary) tumor to the meninges (thin layers of tissue that… (More)
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
Erlotinib is effective for epidermal growth factor receptor (EGFR) mutant lung cancer, but CNS penetration at standard daily… (More)
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Highly Cited
2010
Highly Cited
2010
Leptomeningeal metastases (LM) occur in 5–10% of patients with solid tumors and are associated with a dismal prognosis. We… (More)
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Highly Cited
2007
Highly Cited
2007
The aim of the study was to assess the efficacy of multimodality treatment of patients with Leptomeningeal metastasis (LM) and to… (More)
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Highly Cited
2005
Highly Cited
2005
BACKGROUND Gefitinib is an epidermal growth factor receptor tyrosine kinase inhibitor that induces an early and dramatic response… (More)
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Review
2003
Review
2003
The brain, cranial nerves, leptomeninges, spinal cord, and eye compose the central nervous system (CNS) and are at risk for the… (More)
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Review
1998
Review
1998
Meningeal metastasis occurs in 3–8% of all cancer patients, producing neurologic morbidity and a high mortality. Diagnosis is… (More)
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Highly Cited
1998
Highly Cited
1998
BACKGROUND Leptomeningeal metastases (LM) are increasingly diagnosed as anticancer therapies become more effective and result in… (More)
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Highly Cited
1995
Highly Cited
1995
The diagnosis of leptomeningeal metastasis is often difficult and usually requires the demonstration of malignant cells in the… (More)
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Highly Cited
1990
Highly Cited
1990
We evaluated 14 consecutive patients with leptomeningeal metastasis prospectively, using both T1-weighted (T1W) gadolinium-DTPA… (More)
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Highly Cited
1982
Highly Cited
1982
The clinical findings and response to treatment of leptomeningeal metastases from solid tumors are analyzed in 90 patients… (More)
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