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Metastatic Malignant Neoplasm to the Leptomeninges

Known as: cancer, metastatic to leptomeninges, leptomeningeal carcinoma, leptomeningitis, carcinomatous 
A serious problem that may occur in cancer in which cancer cells spread from the original (primary) tumor to the meninges (thin layers of tissue that… 
National Institutes of Health

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Central Nervous SystemLeptomeningesMeningeal CarcinomatosisMeningeal Leukemia

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2014
Review
2014
Leptomeningeal metastasis: a Response Assessment in Neuro-Oncology critical review of endpoints and response criteria of published randomized clinical trials.
PURPOSE To date, response criteria and optimal methods for assessment of outcome have not been standardized in patients with… 
Review
2010
Review
2010
Leptomeningeal metastases in the MRI era
Background: Diagnosis of leptomeningeal metastasis (LM) has become increasingly frequent. The diagnostic gold standard has been… 
Highly Cited
2005
Highly Cited
2005
High incidence of disease recurrence in the brain and leptomeninges in patients with nonsmall cell lung carcinoma after response to gefitinib
Gefitinib is an epidermal growth factor receptor tyrosine kinase inhibitor that induces an early and dramatic response in 10% of… 
Review
2005
Review
2005
Leptomeningeal metastases from solid malignancy: a review
SummaryLeptomeningeal metastases (LMM) consist of diffuse involvement of the leptomeninges by infiltrating cancer cells. In solid… 
Review
2003
Review
2003
Diagnosis and management of central nervous system metastases from breast cancer.
The brain, cranial nerves, leptomeninges, spinal cord, and eye compose the central nervous system (CNS) and are at risk for the… 
Highly Cited
1999
Highly Cited
1999
The diagnostic accuracy of magnetic resonance imaging and cerebrospinal fluid cytology in leptomeningeal metastasis
Abstract Diagnostic decision making in the case of patients suspected of having leptomeningeal metastasis (LM) can be very… 
Review
1990
Review
1990
Leptomeningeal metastases: Comparison of clinical features and laboratory data of solid tumors, lymphomas and leukemias
We reviewed 63 cases of cytologically confirmed leptomeningeal metastases (LM). 31 (49%) had solid tumors 17 (27%) had leukemia… 
Highly Cited
1990
Highly Cited
1990
Leptomeningeal metastasis
We evaluated 14 consecutive patients with leptomeningeal metastasis prospectively, using both T1-weighted (T1W) gadolinium-DTPA… 
Review
1982
Review
1982
Carcinomatous Leptomeningitis in Small Cell Lung Cancer: A Clinicopathologic Review of the National Cancer Institute Experience
CLM developed in 60 of 526 patients (11%) with SCLC seen at the NCI between August 1969 and June 1980. Life table analysis… 
Review
1978
Review
1978
Spinal subarachnoid metastasis from primary intracranial glioblastoma multiforme
Twenty‐five patients with glioblastoma multiforme were autopsied at our institution in 7 years. Spinal cords were examined in 20… 
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