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Metastasis Suppressor Genes

Known as: Gene, Metastasis Suppressor, Metastasis Suppressor Gene, Genes, Metastasis Suppressor 
A cancer gene that plays a role in the suppression of metastasis, a process whereby cancer spreads from one part of the body to another.
National Institutes of Health

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7 relations
BRMS1 protein, humanHomo sapiensKISS1 protein, humanMetastasis Suppression

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Identification and validation of genes with expression patterns inverse to multiple metastasis suppressor genes in breast cancer cell lines
Metastasis suppressor genes (MSGs) have contributed to an understanding of regulatory pathways unique to the lethal metastatic… 
Highly Cited
2011
Highly Cited
2011
Phosphorylation of RelA/p65 promotes DNMT-1 recruitment to chromatin and represses transcription of the tumor metastasis suppressor gene BRMS1
The majority of patients with lung cancer present with metastatic disease. Chronic inflammation and subsequent activation of… 
Review
2011
Review
2011
Epigenetic modifications of metastasis suppressor genes in colon cancer metastasis
Colon and rectal cancer (colorectal cancer, CRC) is the third most common cancer worldwide. Deaths from CRC account for around 8… 
2010
2010
SERPINB5 and AKAP12 -- Expression and promoter methylation of metastasis suppressor genes in pancreatic ductal adenocarcinoma
BackgroundEarly metastasis and infiltration are survival limiting characteristics of pancreatic ductal adenocarcinoma (PDAC… 
Review
2009
Review
2009
STAT3 as a central regulator of tumor metastases.
Metastasis is a major cause of morbidity and mortality in patients with cancer. The molecular mechanisms that control metastasis… 
Review
2008
Review
2008
The role of metastasis suppressor genes in metastatic dormancy  
Metastasis suppressor genes (MSGs) are defined by their ability to inhibit overt metastasis in a secondary organ without… 
Review
2006
Review
2006
Translational approaches using metastasis suppressor genes
Cancer metastasis is a significant contributor to breast cancer patient morbidity and mortality. In order to develop new anti… 
Highly Cited
2005
Highly Cited
2005
Reduced metastasis-suppressor gene mRNA-expression in breast cancer brain metastases
Purpose Brain metastases are an increasingly common complication in breast cancer patients. The Metastasis Suppressor Genes (MSG… 
Review
2004
Review
2004
Metastasis suppressor genes: a role for raf kinase inhibitor protein (RKIP).
The metastatic cascade is a complicated process that involves many steps from gain of the metastatic phenotype in the primary… 
Review
2004
Review
2004
Molecular biology of prostate cancer
SummaryCarcinoma of the prostate (CaP) is a very prevalent tumor among men. However thus far, relatively little information is… 
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