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Metaplasia

Known as: Metaplasia [Disease/Finding], Metaplastic Change, metaplasis 
Transformation of a mature, normal cell or groups of mature cells to other forms of mature cells. The capacity for malignant transformation of… Expand
National Institutes of Health

Related topics

Related topics

28 relations
Barrett EsophagusBarrett's AdenocarcinomaBladder Squamous Cell CarcinomaCDISC SEND Non-Neoplastic Finding Type Terminology
Expand

Narrower (3)

Biological MetamorphosisMyeloid Metaplasiacervical metaplasia

Broader (1)

Signs and Symptoms

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
Pathogenesis of endometriosis: the genetic/epigenetic theory.
OBJECTIVE To study the pathophysiology of endometriosis. DESIGN Overview of observations on endometriosis. SETTING Not… Expand
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Review
2018
Review
2018
Pathogenesis of uterine adenomyosis: invagination or metaplasia?
Adenomyosis is a commonly diagnosed estrogen-dependent gynecological disorder that causes pelvic pain, abnormal uterine bleeding… Expand
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Highly Cited
2011
Highly Cited
2011
Residual Embryonic Cells as Precursors of a Barrett's-like Metaplasia
Barrett's esophagus is an intestine-like metaplasia and precursor of esophageal adenocarcinoma. Triggered by gastroesophageal… Expand
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Highly Cited
2010
Highly Cited
2010
The Origin and Pathogenesis of Epithelial Ovarian Cancer: A Proposed Unifying Theory
  • R. Kurman, I. Shih
  • The American journal of surgical pathology
  • 2010
    • Corpus ID: 33753425
Ovarian cancer is the most lethal gynecologic malignancy. Efforts at early detection and new therapeutic approaches to reduce… Expand
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Highly Cited
2006
Highly Cited
2006
MPLW515L Is a Novel Somatic Activating Mutation in Myelofibrosis with Myeloid Metaplasia
Background The JAK2V617F allele has recently been identified in patients with polycythemia vera (PV), essential thrombocytosis… Expand
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Highly Cited
2004
Highly Cited
2004
Modulation of notch processing by gamma-secretase inhibitors causes intestinal goblet cell metaplasia and induction of genes known to specify gut secretory lineage differentiation.
It is anticipated that gamma-secretase inhibitors (gamma-Sec-I) that modulate Notch processing will alter differentiation in… Expand
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Highly Cited
1999
Highly Cited
1999
Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production.
Interleukin (IL)-13 is a pleiotropic cytokine produced in large quantities by activated CD4(+) Th2 lymphocytes. To define further… Expand
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Highly Cited
1999
Highly Cited
1999
IL-4 induces mucin gene expression and goblet cell metaplasia in vitro and in vivo.
Goblet cell metaplasia and mucus hypersecretion are important features in the pathogenesis of asthma. The cytokine IL-4 has been… Expand
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Highly Cited
1992
Highly Cited
1992
Cloning of the Ah-receptor cDNA reveals a distinctive ligand-activated transcription factor.
A cDNA encoding the murine Ah receptor (Ahb-1 allele for aromatic hydrocarbon responsiveness) has been isolated and characterized… Expand
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Highly Cited
1990
Highly Cited
1990
Overexpression of TGFα in transgenic mice: Induction of epithelial hyperplasia, pancreatic metaplasia, and carcinoma of the breast
Metallothionein-directed expression of TGF alpha in transgenic mice induced a spectrum of changes in the growth and… Expand
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