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Metabolite Interaction

Metabolite Interaction involves a biophysical interaction with a biological metabolite.
National Institutes of Health

Papers overview

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2016
2016
BACKGROUND AND SCOPE Weight loss success is dependent on the ability to refrain from regaining the lost weight in time. This… Expand
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Review
2015
Review
2015
Thermal stabilization of proteins after ligand binding provides an efficient means to assess the binding of small molecules to… Expand
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2015
2011
2011
Neuron-derived clone 77 (Nur77) is an orphan nuclear receptor with currently no known natural ligands. Here we applied a… Expand
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Highly Cited
2011
Highly Cited
2011
Drug Affinity Responsive Target Stability is a general methodology for identifying and studying protein-ligand interactions. The… Expand
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2009
2009
We present a simplified stochastic model to investigate the mechanisms of action of tramadol, a centrally acting analgesic, used… Expand
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Highly Cited
2009
Highly Cited
2009
Metabolite concentrations can regulate gene expression, which can in turn regulate metabolic activity. The extent to which… Expand
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Highly Cited
2009
Highly Cited
2009
Identifying the molecular targets for the beneficial or detrimental effects of small-molecule drugs is an important and currently… Expand
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Highly Cited
2009
Highly Cited
2009
Genome sequencing dramatically increased our ability to understand cellular response to perturbation. Integrating system-wide… Expand
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